Abstract
We present an operationally simple iterative coupling strategy for the synthesis of oligomeric homo- and hetero[n]rotaxanes with precise control over the position of each macrocycle. The exceptional yield of the AT-CuAAC reaction, combined with optimized conditions that allow the rapid synthesis of the target oligomers, opens the door to the study of precision-engineered oligomeric interlocked molecules.
Original language | English |
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Pages (from-to) | 16329-16336 |
Number of pages | 8 |
Journal | Journal of the American Chemical Society |
Volume | 138 |
Issue number | 50 |
DOIs | |
Publication status | Published - 21 Dec 2016 |
Bibliographical note
Funding Information:The authors are grateful to Fluorochem for the gift of reagents. High-resolution mass spectrometry analysis was carried out by the EPSRC National Spectrometry Facility. This work was supported financially by the Royal Society, the European Union, and the EPSRC (EP/J01981X/1). This project has received funding from the European Unions Horizon 2020 research and innovation programme under the Marie Sk?odowska-Curie grant agreement no. 660731. J.E.M.L. is an EU Marie Sklodowska-Curie Fellow. S.M.G. is a Royal Society Research Fellow.
Publisher Copyright:
© 2016 American Chemical Society.
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Biochemistry
- Colloid and Surface Chemistry