Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

Judit Galcera; Tomislav Friščić; Elies Molins; William Jones

doi:10.1039/c2ce26791h

Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

Judit Galcera^*
, Tomislav Friščić
, Elies Molins
, William Jones

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.

Original language	English
Pages (from-to)	1332-1338
Number of pages	7
Journal	CrystEngComm
Volume	15
Issue number	7
DOIs	https://doi.org/10.1039/c2ce26791h
Publication status	Published - 21 Feb 2013

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

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10.1039/c2ce26791h

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title = "Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion",

abstract = "We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.",

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AU - Galcera, Judit

AU - Friščić, Tomislav

AU - Molins, Elies

AU - Jones, William

PY - 2013/2/21

Y1 - 2013/2/21

N2 - We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.

AB - We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.

UR - https://www.scopus.com/pages/publications/84872709691

U2 - 10.1039/c2ce26791h

DO - 10.1039/c2ce26791h

M3 - Article

AN - SCOPUS:84872709691

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JO - CrystEngComm

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IS - 7

ER -

Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

Abstract

ASJC Scopus subject areas

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