Is immunosenescence influenced by our lifetime “dose” of exercise?

Research output: Contribution to journalArticlepeer-review


The age-associated decline in immune function, referred to as immunosenescence, is well characterised within the adaptive immune system, and in particular, among T cells. Hallmarks of immunosenescence measured in the T cell pool, include low numbers and proportions of naïve cells, high numbers and proportions of late-stage differentiated effector memory cells, poor proliferative responses to mitogens, and a CD4:CD8 ratio
Original languageEnglish
Pages (from-to)581-602
Number of pages22
Issue number3
Publication statusPublished - 1 Jun 2016


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