IpsA, a novel LacI-type regulator, is required for inositol-derived lipid formation in Corynebacteria and Mycobacteria

Meike Baumgart, Kerstin Luder, Shipra Grover, Cornelia Gätgens, Gurdyal S Besra, Julia Frunzke

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)
258 Downloads (Pure)

Abstract

The development of new drugs against tuberculosis and diphtheria is focused on disrupting the biogenesis of the cell wall, the unique architecture of which confers resistance against current therapies. The enzymatic pathways involved in the synthesis of the cell wall by these pathogens are well understood but the underlying regulatory mechanisms are largely unknown.
Original languageEnglish
Article number122
JournalBMC Biology
Volume11
DOIs
Publication statusPublished - 30 Dec 2013

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