Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture

Enrico Amico; Pieter Van Mierlo; Daniele Marinazzo; Steven Laureys

doi:10.1109/EMBC.2015.7319611

Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture

Enrico Amico, Pieter Van Mierlo, Daniele Marinazzo, Steven Laureys

Mathematics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Transcranial magnetic stimulation (TMS) has been used for more than 20 years to investigate connectivity and plasticity in the human cortex. By combining TMS with high-density electroencephalography (hd-EEG), one can stimulate any cortical area and measure the effects produced by this perturbation in the rest of the cerebral cortex. The purpose of this paper is to investigate changes of information flow in the brain after TMS from a functional and structural perspective, using multimodal modeling of source reconstructed TMS/hd-EEG recordings and DTI tractography. We prove how brain dynamics induced by TMS is constrained and driven by its structure, at different spatial and temporal scales, especially when considering cross-frequency interactions. These results shed light on the function-structure organization of the brain network at the global level, and on the huge variety of information contained in it.

Original language	English
Title of host publication	2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Pages	5396-5399
Number of pages	4
ISBN (Electronic)	9781424492718, 9781424492701 (DVD)
DOIs	https://doi.org/10.1109/EMBC.2015.7319611
Publication status	Published - 5 Nov 2015
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: 25 Aug 2015 → 29 Aug 2015

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Publisher	IEEE
ISSN (Print)	1094-687X
ISSN (Electronic)	1558-4615

Conference

Conference	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country/Territory	Italy
City	Milan
Period	25/08/15 → 29/08/15

Bibliographical note

Publisher Copyright:
© 2015 IEEE.

Keywords

Electroencephalography
Brain modeling
Image reconstruction
Diffusion tensor imaging
Adaptation models
Magnetic stimulation

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Access to Document

10.1109/EMBC.2015.7319611

Cite this

Amico, E., Van Mierlo, P., Marinazzo, D., & Laureys, S. (2015). Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (pp. 5396-5399). Article 7319611 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society). Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/EMBC.2015.7319611

Amico, Enrico ; Van Mierlo, Pieter ; Marinazzo, Daniele et al. / Investigating dynamical information transfer in the brain following a TMS pulse : Insights from structural architecture. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Institute of Electrical and Electronics Engineers (IEEE), 2015. pp. 5396-5399 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society).

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title = "Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture",

abstract = "Transcranial magnetic stimulation (TMS) has been used for more than 20 years to investigate connectivity and plasticity in the human cortex. By combining TMS with high-density electroencephalography (hd-EEG), one can stimulate any cortical area and measure the effects produced by this perturbation in the rest of the cerebral cortex. The purpose of this paper is to investigate changes of information flow in the brain after TMS from a functional and structural perspective, using multimodal modeling of source reconstructed TMS/hd-EEG recordings and DTI tractography. We prove how brain dynamics induced by TMS is constrained and driven by its structure, at different spatial and temporal scales, especially when considering cross-frequency interactions. These results shed light on the function-structure organization of the brain network at the global level, and on the huge variety of information contained in it.",

keywords = "Electroencephalography, Brain modeling, Image reconstruction, Diffusion tensor imaging, Adaptation models, Magnetic stimulation",

author = "Enrico Amico and {Van Mierlo}, Pieter and Daniele Marinazzo and Steven Laureys",

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doi = "10.1109/EMBC.2015.7319611",

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Amico, E, Van Mierlo, P, Marinazzo, D & Laureys, S 2015, Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)., 7319611, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Institute of Electrical and Electronics Engineers (IEEE), pp. 5396-5399, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 25/08/15. https://doi.org/10.1109/EMBC.2015.7319611

Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture. / Amico, Enrico; Van Mierlo, Pieter; Marinazzo, Daniele et al.
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Institute of Electrical and Electronics Engineers (IEEE), 2015. p. 5396-5399 7319611 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - Transcranial magnetic stimulation (TMS) has been used for more than 20 years to investigate connectivity and plasticity in the human cortex. By combining TMS with high-density electroencephalography (hd-EEG), one can stimulate any cortical area and measure the effects produced by this perturbation in the rest of the cerebral cortex. The purpose of this paper is to investigate changes of information flow in the brain after TMS from a functional and structural perspective, using multimodal modeling of source reconstructed TMS/hd-EEG recordings and DTI tractography. We prove how brain dynamics induced by TMS is constrained and driven by its structure, at different spatial and temporal scales, especially when considering cross-frequency interactions. These results shed light on the function-structure organization of the brain network at the global level, and on the huge variety of information contained in it.

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Amico E, Van Mierlo P, Marinazzo D, Laureys S. Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Institute of Electrical and Electronics Engineers (IEEE). 2015. p. 5396-5399. 7319611. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society). doi: 10.1109/EMBC.2015.7319611

Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture

Abstract

Publication series

Conference

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this