Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival

DM Sze, Kai-Michael Toellner, Carola Garcia de Vineusa de la Concha, Dale Taylor, Ian MacLennan

Research output: Contribution to journalArticle

224 Citations (Scopus)

Abstract

B cells recruited into splenic antibody responses grow exponentially, either in extrafollicular foci as plasmablasts, or in follicles where they form germinal centers. Both responses yield plasma cells. Although many splenic plasma cells survive
Original languageEnglish
Pages (from-to)813-21
Number of pages9
JournalThe Journal of Experimental Medicine
Volume192
Issue number6
DOIs
Publication statusPublished - 11 Sept 2000

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