Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction: role of bile acids

N Kalia; J Hardcastle; C Keating; L Grasa; C Keating; P Pelegrin; K D Bardhan; D Grundy

Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction: role of bile acids

N Kalia
, J Hardcastle
, C Keating
, L Grasa
, C Keating
, P Pelegrin
, K D Bardhan
, D Grundy

Cardiovascular Sciences

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Observations showing that bile acid malabsorption is frequent in irritable bowel syndrome (IBS) suggest that alterations in bile acid-induced secretion and absorption could contribute to IBS-associated diarrhoea. The secretory response to bile acids, fluid transport and bile absorption was examined in intestinal tissues from a Trichinella spiralis mouse model of postinfectious gut dysfunction in vitro. Changes in the protein expression of apical sodium-dependent bile acid transporter (ASBT) were also measured.

Original language	English
Pages (from-to)	41-9
Number of pages	9
Journal	Gut
Volume	57
Issue number	1
Publication status	Published - 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction: role of bile acids",

abstract = "Observations showing that bile acid malabsorption is frequent in irritable bowel syndrome (IBS) suggest that alterations in bile acid-induced secretion and absorption could contribute to IBS-associated diarrhoea. The secretory response to bile acids, fluid transport and bile absorption was examined in intestinal tissues from a Trichinella spiralis mouse model of postinfectious gut dysfunction in vitro. Changes in the protein expression of apical sodium-dependent bile acid transporter (ASBT) were also measured.",

author = "N Kalia and J Hardcastle and C Keating and L Grasa and C Keating and P Pelegrin and Bardhan, \{K D\} and D Grundy",

year = "2008",

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issn = "1468-3288",

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T1 - Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction

T2 - role of bile acids

AU - Kalia, N

AU - Hardcastle, J

AU - Keating, C

AU - Grasa, L

AU - Keating, C

AU - Pelegrin, P

AU - Bardhan, K D

AU - Grundy, D

PY - 2008

Y1 - 2008

N2 - Observations showing that bile acid malabsorption is frequent in irritable bowel syndrome (IBS) suggest that alterations in bile acid-induced secretion and absorption could contribute to IBS-associated diarrhoea. The secretory response to bile acids, fluid transport and bile absorption was examined in intestinal tissues from a Trichinella spiralis mouse model of postinfectious gut dysfunction in vitro. Changes in the protein expression of apical sodium-dependent bile acid transporter (ASBT) were also measured.

AB - Observations showing that bile acid malabsorption is frequent in irritable bowel syndrome (IBS) suggest that alterations in bile acid-induced secretion and absorption could contribute to IBS-associated diarrhoea. The secretory response to bile acids, fluid transport and bile absorption was examined in intestinal tissues from a Trichinella spiralis mouse model of postinfectious gut dysfunction in vitro. Changes in the protein expression of apical sodium-dependent bile acid transporter (ASBT) were also measured.

M3 - Article

C2 - 17675326

SN - 1468-3288

VL - 57

SP - 41

EP - 49

JO - Gut

JF - Gut

IS - 1

ER -

Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction: role of bile acids

Abstract

UN SDGs

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