Abstract
Observations showing that bile acid malabsorption is frequent in irritable bowel syndrome (IBS) suggest that alterations in bile acid-induced secretion and absorption could contribute to IBS-associated diarrhoea. The secretory response to bile acids, fluid transport and bile absorption was examined in intestinal tissues from a Trichinella spiralis mouse model of postinfectious gut dysfunction in vitro. Changes in the protein expression of apical sodium-dependent bile acid transporter (ASBT) were also measured.
Original language | English |
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Pages (from-to) | 41-9 |
Number of pages | 9 |
Journal | Gut |
Volume | 57 |
Issue number | 1 |
Publication status | Published - 2008 |