Interventions to reduce the risk of ovarian and fallopian tube cancer:: A European Menopause and Andropause Society Postition Statement

Faustino R. Pérez-lópez; Iuliana Ceausu; Herman Depypere; Sean Kehoe; Irene Lambrinoudaki; Alfred Mueck; Levent M. Senturk; Tommaso Simoncini; John C. Stevenson; Petra Stute; Margaret Rees

doi:10.1016/j.maturitas.2017.03.003

Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Postition Statement

Faustino R. Pérez-lópez, Iuliana Ceausu, Herman Depypere, Sean Kehoe, Irene Lambrinoudaki, Alfred Mueck, Levent M. Senturk, Tommaso Simoncini, John C. Stevenson, Petra Stute, Margaret Rees

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

142 Downloads (Pure)

Abstract

Background: Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches.

Aims: To examine risk factors and risk-reducing strategies for both sporadic and familial tumors.

Materials and methods: Literature review and consensus of expert opinion.

Results and conclusions: In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer. Opportunistic bilateral salpingo-oophorectomy and bilateral salpingectomy may also prevent epithelial ovarian cancer. In premenopausal women, bilateral salpingectomy should be preferred to tubal ligation, and be performed when hysterectomy is carried out for benign uterine disease. Hysterectomy and the use of combined oral contraceptives and non-steroid anti-inflammatory drugs are also recognized to reduce the risk of ovarian cancer, as do the prevention of obesity and smoking cessation.

Original language	English
Journal	Maturitas
Early online date	15 Mar 2017
DOIs	https://doi.org/10.1016/j.maturitas.2017.03.003
Publication status	E-pub ahead of print - 15 Mar 2017

Keywords

Ovarian cancer
Fallopian tubes cancer
Ovarian borderline tumors
BRCA gene mutation
Bilateral salpingectomy
Bilateral oophorectomy
Combined oral contraceptives
Hysterectomy
Non-steroid anti-inflammatory drugs
Obesity
Smoking

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.maturitas.2017.03.003Licence: None: All rights reserved

Perez-Lopez_et_al_Interventions_to_reduce_the_risk_Mauturitas_2017Accepted author manuscript, 373 KBLicence: Creative Commons: Attribution-NonCommercial-NoDerivs (CC BY-NC-ND)

http://www.sciencedirect.com/science/article/pii/S0378512217301342Licence: None: All rights reserved

Cite this

Pérez-lópez, F. R., Ceausu, I., Depypere, H., Kehoe, S., Lambrinoudaki, I., Mueck, A., Senturk, L. M., Simoncini, T., Stevenson, J. C., Stute, P., & Rees, M. (2017). Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Postition Statement. Maturitas. Advance online publication. https://doi.org/10.1016/j.maturitas.2017.03.003

@article{91748c3ddc6f4757973ffcb47fdb9326,

title = "Interventions to reduce the risk of ovarian and fallopian tube cancer:: A European Menopause and Andropause Society Postition Statement",

abstract = "Background: Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches.Aims: To examine risk factors and risk-reducing strategies for both sporadic and familial tumors.Materials and methods: Literature review and consensus of expert opinion.Results and conclusions: In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer. Opportunistic bilateral salpingo-oophorectomy and bilateral salpingectomy may also prevent epithelial ovarian cancer. In premenopausal women, bilateral salpingectomy should be preferred to tubal ligation, and be performed when hysterectomy is carried out for benign uterine disease. Hysterectomy and the use of combined oral contraceptives and non-steroid anti-inflammatory drugs are also recognized to reduce the risk of ovarian cancer, as do the prevention of obesity and smoking cessation.",

keywords = "Ovarian cancer , Fallopian tubes cancer , Ovarian borderline tumors , BRCA gene mutation , Bilateral salpingectomy , Bilateral oophorectomy , Combined oral contraceptives , Hysterectomy , Non-steroid anti-inflammatory drugs , Obesity , Smoking",

author = "P{\'e}rez-l{\'o}pez, {Faustino R.} and Iuliana Ceausu and Herman Depypere and Sean Kehoe and Irene Lambrinoudaki and Alfred Mueck and Senturk, {Levent M.} and Tommaso Simoncini and Stevenson, {John C.} and Petra Stute and Margaret Rees",

year = "2017",

month = mar,

day = "15",

doi = "10.1016/j.maturitas.2017.03.003",

language = "English",

journal = "Maturitas",

issn = "0378-5122",

publisher = "Elsevier",

}

TY - JOUR

T1 - Interventions to reduce the risk of ovarian and fallopian tube cancer:

T2 - A European Menopause and Andropause Society Postition Statement

AU - Pérez-lópez, Faustino R.

AU - Ceausu, Iuliana

AU - Depypere, Herman

AU - Kehoe, Sean

AU - Lambrinoudaki, Irene

AU - Mueck, Alfred

AU - Senturk, Levent M.

AU - Simoncini, Tommaso

AU - Stevenson, John C.

AU - Stute, Petra

AU - Rees, Margaret

PY - 2017/3/15

Y1 - 2017/3/15

N2 - Background: Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches.Aims: To examine risk factors and risk-reducing strategies for both sporadic and familial tumors.Materials and methods: Literature review and consensus of expert opinion.Results and conclusions: In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer. Opportunistic bilateral salpingo-oophorectomy and bilateral salpingectomy may also prevent epithelial ovarian cancer. In premenopausal women, bilateral salpingectomy should be preferred to tubal ligation, and be performed when hysterectomy is carried out for benign uterine disease. Hysterectomy and the use of combined oral contraceptives and non-steroid anti-inflammatory drugs are also recognized to reduce the risk of ovarian cancer, as do the prevention of obesity and smoking cessation.

AB - Background: Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches.Aims: To examine risk factors and risk-reducing strategies for both sporadic and familial tumors.Materials and methods: Literature review and consensus of expert opinion.Results and conclusions: In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer. Opportunistic bilateral salpingo-oophorectomy and bilateral salpingectomy may also prevent epithelial ovarian cancer. In premenopausal women, bilateral salpingectomy should be preferred to tubal ligation, and be performed when hysterectomy is carried out for benign uterine disease. Hysterectomy and the use of combined oral contraceptives and non-steroid anti-inflammatory drugs are also recognized to reduce the risk of ovarian cancer, as do the prevention of obesity and smoking cessation.

KW - Ovarian cancer

KW - Fallopian tubes cancer

KW - Ovarian borderline tumors

KW - BRCA gene mutation

KW - Bilateral salpingectomy

KW - Bilateral oophorectomy

KW - Combined oral contraceptives

KW - Hysterectomy

KW - Non-steroid anti-inflammatory drugs

KW - Obesity

KW - Smoking

U2 - 10.1016/j.maturitas.2017.03.003

DO - 10.1016/j.maturitas.2017.03.003

M3 - Article

SN - 0378-5122

JO - Maturitas

JF - Maturitas

ER -