Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus

A I Blakemore; J K Tarlow; M J Cork; C Gordon; P Emery; G W Duff

Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus

A I Blakemore
, J K Tarlow
, M J Cork
, C Gordon
, P Emery
, G W Duff

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

252 Citations (Scopus)

Abstract

We have previously described associations between an allele of the interleukin-1 receptor antagonist gene (IL1RN) and several inflammatory diseases. In this study we tested the IL1RN gene as a possible marker in patients with systemic lupus erythematosus (SLE).

Original language	English
Pages (from-to)	1380-5
Number of pages	6
Journal	Arthritis & Rheumatism
Volume	37
Issue number	9
Publication status	Published - Sept 1994

Keywords

Base Sequence
Humans
Lupus Erythematosus, Discoid
Lupus Erythematosus, Systemic
Molecular Probes
Molecular Sequence Data
Photosensitivity Disorders
Polymorphism, Genetic
Receptors, Interleukin-1
Severity of Illness Index

Cite this

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title = "Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus",

abstract = "We have previously described associations between an allele of the interleukin-1 receptor antagonist gene (IL1RN) and several inflammatory diseases. In this study we tested the IL1RN gene as a possible marker in patients with systemic lupus erythematosus (SLE).",

keywords = "Base Sequence, Humans, Lupus Erythematosus, Discoid, Lupus Erythematosus, Systemic, Molecular Probes, Molecular Sequence Data, Photosensitivity Disorders, Polymorphism, Genetic, Receptors, Interleukin-1, Severity of Illness Index",

author = "Blakemore, \{A I\} and Tarlow, \{J K\} and Cork, \{M J\} and C Gordon and P Emery and Duff, \{G W\}",

year = "1994",

month = sep,

language = "English",

volume = "37",

pages = "1380--5",

journal = "Arthritis \& Rheumatism",

issn = "0004-3591",

publisher = "Wiley",

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TY - JOUR

T1 - Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus

AU - Blakemore, A I

AU - Tarlow, J K

AU - Cork, M J

AU - Gordon, C

AU - Emery, P

AU - Duff, G W

PY - 1994/9

Y1 - 1994/9

N2 - We have previously described associations between an allele of the interleukin-1 receptor antagonist gene (IL1RN) and several inflammatory diseases. In this study we tested the IL1RN gene as a possible marker in patients with systemic lupus erythematosus (SLE).

AB - We have previously described associations between an allele of the interleukin-1 receptor antagonist gene (IL1RN) and several inflammatory diseases. In this study we tested the IL1RN gene as a possible marker in patients with systemic lupus erythematosus (SLE).

KW - Base Sequence

KW - Humans

KW - Lupus Erythematosus, Discoid

KW - Lupus Erythematosus, Systemic

KW - Molecular Probes

KW - Molecular Sequence Data

KW - Photosensitivity Disorders

KW - Polymorphism, Genetic

KW - Receptors, Interleukin-1

KW - Severity of Illness Index

M3 - Article

C2 - 7945503

SN - 0004-3591

VL - 37

SP - 1380

EP - 1385

JO - Arthritis & Rheumatism

JF - Arthritis & Rheumatism

IS - 9

ER -

Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus

Abstract

Keywords

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