Inositol phosphates: a remarkably versatile enzyme

Robert Michell

Research output: Contribution to journalArticle

6 Citations (Scopus)


Ins(3,4,5,6)P(4) is an inhibitor of Ca(2+)-activated Cl(-) channels, but further understanding has been hindered by ignorance of how it is made in cells. It now transpires that one protein with ATP-dependent kinase and phosphatase activities interconverts Ins(3,4,5,6)P(4) and Ins(1,3,4,5,6)P(5), as well as several other inositol polyphosphates.
Original languageEnglish
Pages (from-to)R313-5
JournalCurrent Biology
Issue number9
Publication statusPublished - 1 Apr 2002


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