Abstract
Thyroid hormones are essential for maintaining a pregnancy and optimal fetal neurological development. Pregnancy places additional demands on the thyroid axis and around 5% of women who have their thyroid function checked during gestation will have borderline low thyroid function (subclinical hypothyroidism or isolated hypothyroxinemia) identified. These borderline low thyroid states are associated with adverse obstetric and offspring outcomes. Whilst it is well established that overt hypothyroidism requires treatment with levothyroxine, it is less clear whether there is any benefit of treating borderline low thyroid states. This review summarizes the potential indications for treatment of subclinical hypothyroidism and isolated hypothyroxinemia.
| Original language | English |
|---|---|
| Article number | 101436 |
| Journal | Best Practice and Research: Clinical Endocrinology and Metabolism |
| Volume | 34 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jul 2020 |
Bibliographical note
Publisher Copyright:© 2020
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- isolated hypothyroxinemia
- levothyroxine
- pregnancy
- screening
- subclinical hypothyroidism
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology
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