IncP plasmid carrying the colistin resistance gene mcr-1 in Klebsiella pneumoniae from hospital sewage

Feifei Zhao, Yu Feng, Xiaoju Lü, Alan McNally, Zhiyong Zong

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46 Citations (Scopus)
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Abstract

A Klebsiella pneumoniae strain of ST313 recovered from hospital sewage was found to carry the plasmid-borne colistin resistance gene mcr-1, which was bracketed by two copies of the insertion sequence ISApl1 on a 57-kb self-transmissible IncP type plasmid of a new IncP-1 clade. The carriage of mcr-1 on a self-transmissible broad-host-range plasmid highlights that mcr-1 has the potential to be spread beyond the Enterobacteriaceae.

Original languageEnglish
Article numbere02229
Number of pages6
JournalAntimicrobial Agents and Chemotherapy
Volume61
DOIs
Publication statusPublished - 24 Jan 2017

Keywords

  • colistin resistance
  • mcr-1
  • sewage
  • Klebsiella pneumoniae

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