In situ 4D tomography image analysis framework to follow sintering within 3D-printed glass scaffolds

Achintha Kondarage; Gowsihan Poologasundarampillai; Amy Nommeots-Nomm; Peter D. Lee; Thilina D Lalitharatne; Nuwan Nanayakkara; Julian R Jones; Angelo Karunaratne

doi:10.1111/jace.18182

In situ 4D tomography image analysis framework to follow sintering within 3D-printed glass scaffolds

Achintha Kondarage, Gowsihan Poologasundarampillai, Amy Nommeots-Nomm, Peter D. Lee, Thilina D Lalitharatne, Nuwan Nanayakkara, Julian R Jones, Angelo Karunaratne

Dentistry

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Abstract

We propose a novel image analysis framework to automate analysis of X-ray microtomography images of sintering ceramics and glasses, using open-source toolkits and machine learning. Additive manufacturing (AM) of glasses and ceramics usually requires sintering of green bodies. Sintering causes shrinkage, which presents a challenge for controlling the metrology of the final architecture. Therefore, being able to monitor sintering in 3D over time (termed 4D) is important when developing new porous ceramics or glasses. Synchrotron X-ray tomographic imaging allows in situ, real-time capture of the sintering process at both micro and macro scales using a furnace rig, facilitating 4D quantitative analysis of the process. The proposed image analysis framework is capable of tracking and quantifying the densification of glass or ceramic particles within multiple volumes of interest (VOIs) along with structural changes over time using 4D image data. The framework is demonstrated by 4D quantitative analysis of bioactive glass ICIE16 within a 3D-printed scaffold. Here, densification of glass particles within 3 VOIs were tracked and quantified along with diameter change of struts and interstrut pore size over the 3D image series, delivering new insights on the sintering mechanism of ICIE16 bioactive glass particles in both micro and macro scales.

Original language	English
Pages (from-to)	1671-1684
Number of pages	14
Journal	Journal of the American Ceramic Society
Volume	105
Issue number	3
Early online date	21 Oct 2021
DOIs	https://doi.org/10.1111/jace.18182
Publication status	Published - Mar 2022

Bibliographical note

Funding Information:
This research was funded by the NIHR Global Health Research (grant number 1613745: NIHR Group on POsT Conflict Trauma in Sri Lanka; PrOTeCT). The 3D printer used in this work was funded via an EPSRC Grant for Graphene 3D networks (EP/K01658X/1). Funding for A.N‐.N. was provided by RCaH‐EP/I02249X/1, and the “Laura” furnace was developed under the grant NE/M013561/. GP acknowledges funding from the EPSRC grant EP/M023877/1 and PDL acknowledges funding from the MRC ImagingBioPro grant (MR/R025673/1), the Research Complex at Harwell and Royal Academy of Engineering (CiET1819/10). The experiment was performed on the Branchline I13‐2 of the Diamond Light Source synchrotron in Oxfordshire, UK, and partly funded by the MT13241: Collaboration Proposal 1809.

Publisher Copyright:
© 2021 The Authors. Journal of the American Ceramic Society published by Wiley Periodicals LLC on behalf of American Ceramic Society

Keywords

X-ray computed tomography
bioactive glass
bioceramics
image analysis
sintering

ASJC Scopus subject areas

Ceramics and Composites
Materials Chemistry

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Cite this

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title = "In situ 4D tomography image analysis framework to follow sintering within 3D-printed glass scaffolds",

abstract = "We propose a novel image analysis framework to automate analysis of X-ray microtomography images of sintering ceramics and glasses, using open-source toolkits and machine learning. Additive manufacturing (AM) of glasses and ceramics usually requires sintering of green bodies. Sintering causes shrinkage, which presents a challenge for controlling the metrology of the final architecture. Therefore, being able to monitor sintering in 3D over time (termed 4D) is important when developing new porous ceramics or glasses. Synchrotron X-ray tomographic imaging allows in situ, real-time capture of the sintering process at both micro and macro scales using a furnace rig, facilitating 4D quantitative analysis of the process. The proposed image analysis framework is capable of tracking and quantifying the densification of glass or ceramic particles within multiple volumes of interest (VOIs) along with structural changes over time using 4D image data. The framework is demonstrated by 4D quantitative analysis of bioactive glass ICIE16 within a 3D-printed scaffold. Here, densification of glass particles within 3 VOIs were tracked and quantified along with diameter change of struts and interstrut pore size over the 3D image series, delivering new insights on the sintering mechanism of ICIE16 bioactive glass particles in both micro and macro scales.",

keywords = "X-ray computed tomography, bioactive glass, bioceramics, image analysis, sintering",

author = "Achintha Kondarage and Gowsihan Poologasundarampillai and Amy Nommeots-Nomm and Lee, {Peter D.} and Lalitharatne, {Thilina D} and Nuwan Nanayakkara and Jones, {Julian R} and Angelo Karunaratne",

note = "Funding Information: This research was funded by the NIHR Global Health Research (grant number 1613745: NIHR Group on POsT Conflict Trauma in Sri Lanka; PrOTeCT). The 3D printer used in this work was funded via an EPSRC Grant for Graphene 3D networks (EP/K01658X/1). Funding for A.N‐.N. was provided by RCaH‐EP/I02249X/1, and the “Laura” furnace was developed under the grant NE/M013561/. GP acknowledges funding from the EPSRC grant EP/M023877/1 and PDL acknowledges funding from the MRC ImagingBioPro grant (MR/R025673/1), the Research Complex at Harwell and Royal Academy of Engineering (CiET1819/10). The experiment was performed on the Branchline I13‐2 of the Diamond Light Source synchrotron in Oxfordshire, UK, and partly funded by the MT13241: Collaboration Proposal 1809. Publisher Copyright: {\textcopyright} 2021 The Authors. Journal of the American Ceramic Society published by Wiley Periodicals LLC on behalf of American Ceramic Society",

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AU - Kondarage, Achintha

AU - Poologasundarampillai, Gowsihan

AU - Nommeots-Nomm, Amy

AU - Lee, Peter D.

AU - Lalitharatne, Thilina D

AU - Nanayakkara, Nuwan

AU - Jones, Julian R

AU - Karunaratne, Angelo

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N2 - We propose a novel image analysis framework to automate analysis of X-ray microtomography images of sintering ceramics and glasses, using open-source toolkits and machine learning. Additive manufacturing (AM) of glasses and ceramics usually requires sintering of green bodies. Sintering causes shrinkage, which presents a challenge for controlling the metrology of the final architecture. Therefore, being able to monitor sintering in 3D over time (termed 4D) is important when developing new porous ceramics or glasses. Synchrotron X-ray tomographic imaging allows in situ, real-time capture of the sintering process at both micro and macro scales using a furnace rig, facilitating 4D quantitative analysis of the process. The proposed image analysis framework is capable of tracking and quantifying the densification of glass or ceramic particles within multiple volumes of interest (VOIs) along with structural changes over time using 4D image data. The framework is demonstrated by 4D quantitative analysis of bioactive glass ICIE16 within a 3D-printed scaffold. Here, densification of glass particles within 3 VOIs were tracked and quantified along with diameter change of struts and interstrut pore size over the 3D image series, delivering new insights on the sintering mechanism of ICIE16 bioactive glass particles in both micro and macro scales.

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In situ 4D tomography image analysis framework to follow sintering within 3D-printed glass scaffolds

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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