In search of an "autophagomometer"

David C Rubinsztein; Ana Maria Cuervo; Brinda Ravikumar; Sovan Sarkar; Viktor Korolchuk; Susmita Kaushik; Daniel J Klionsky

In search of an "autophagomometer"

David C Rubinsztein
, Ana Maria Cuervo
, Brinda Ravikumar
, Sovan Sarkar
, Viktor Korolchuk
, Susmita Kaushik
, Daniel J Klionsky

Cancer and Genomic Sciences

Research output: Contribution to journal › Article

414 Citations (Scopus)

Abstract

Recent years have seen the realization that macroautophagy (which we will call autophagy) is not only important in yeast but is necessary for diverse functions in plants and animals. Importantly, autophagy can have an impact on human pathologies including infectious diseases, cancers, and neurodegenerative conditions. Thus, we need to be able to measure autophagy accurately in order to understand how it can be regulated physiologically and with exogenous agents.

Original language	English
Pages (from-to)	585-9
Number of pages	5
Journal	Autophagy
Volume	5
Issue number	5
Publication status	Published - Jul 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Animals
Autophagy
Humans
Macrolides
Microtubule-Associated Proteins
Phagosomes

Cite this

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abstract = "Recent years have seen the realization that macroautophagy (which we will call autophagy) is not only important in yeast but is necessary for diverse functions in plants and animals. Importantly, autophagy can have an impact on human pathologies including infectious diseases, cancers, and neurodegenerative conditions. Thus, we need to be able to measure autophagy accurately in order to understand how it can be regulated physiologically and with exogenous agents.",

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AU - Rubinsztein, David C

AU - Cuervo, Ana Maria

AU - Ravikumar, Brinda

AU - Sarkar, Sovan

AU - Korolchuk, Viktor

AU - Kaushik, Susmita

AU - Klionsky, Daniel J

PY - 2009/7

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N2 - Recent years have seen the realization that macroautophagy (which we will call autophagy) is not only important in yeast but is necessary for diverse functions in plants and animals. Importantly, autophagy can have an impact on human pathologies including infectious diseases, cancers, and neurodegenerative conditions. Thus, we need to be able to measure autophagy accurately in order to understand how it can be regulated physiologically and with exogenous agents.

AB - Recent years have seen the realization that macroautophagy (which we will call autophagy) is not only important in yeast but is necessary for diverse functions in plants and animals. Importantly, autophagy can have an impact on human pathologies including infectious diseases, cancers, and neurodegenerative conditions. Thus, we need to be able to measure autophagy accurately in order to understand how it can be regulated physiologically and with exogenous agents.

KW - Animals

KW - Autophagy

KW - Humans

KW - Macrolides

KW - Microtubule-Associated Proteins

KW - Phagosomes

M3 - Article

C2 - 19411822

SN - 1554-8627

VL - 5

SP - 585

EP - 589

JO - Autophagy

JF - Autophagy

IS - 5

ER -

In search of an "autophagomometer"

Abstract

UN SDGs

Keywords

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Cite this