Improving therapeutic synergy score predictions with adverse effects using multi-task heterogeneous network learning

Keyphrases

• Adverse Effect Prediction 10%
• Adverse Effects 100%
• Anticancer Drugs 10%
• Auxiliary Task 10%
• Clinical Observation 10%
• Combination Effect 10%
• Computational Methods 10%
• Dasatinib 10%
• Drug Combination 20%
• Drug Interactions 20%
• Drug Pair 10%
• Effect Prediction 50%
• Heterogeneous Network Embedding 20%
• Heterogeneous Networks 100%
• Interaction Dataset 10%
• Learning Methods 10%
• Learning Problems 10%
• Learning Task 10%
• Mechanism of Action 10%
• Mechanism of Drug Action 10%
• Multi-task 100%
• Networked Learning 100%
• Pharmacological Therapy 10%
• Prediction Problems 10%
• Score Prediction 100%
• Single-task Learning 10%
• Synergy Index 100%
• Therapeutic Effect 100%

Neuroscience

• Adverse Effect 100%
• Anticarcinogen 12%
• Combination Drug 25%
• Dasatinib 12%
• Learning Disabilities 12%
• Vincristine 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Drug Combination 10%