Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

Martin Rowe; Jianmin Zuo

doi:10.1016/j.micinf.2009.12.001

Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

Martin Rowe, Jianmin Zuo

Cancer and Genomic Sciences

Research output: Contribution to journal › Review article › peer-review

34 Citations (Scopus)

Abstract

Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation

Original language	English
Pages (from-to)	173-181
Number of pages	9
Journal	Microbes and Infection
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/j.micinf.2009.12.001
Publication status	Published - 1 Mar 2010

Keywords

Immune-evasion
Tumour virus
Epstein-Barr virus
Herpesvirus
Immune response
Antigen presentation

Access to Document

10.1016/j.micinf.2009.12.001Licence: Creative Commons: Attribution (CC BY)

http://dx.doi.org/10.1016/j.micinf.2009.12.001Licence: Creative Commons: Attribution (CC BY)

Cite this

@article{b50c319c4b9946dab0cf66c6a16cd043,

title = "Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity",

abstract = "Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation",

keywords = "Immune-evasion, Tumour virus, Epstein-Barr virus, Herpesvirus, Immune response, Antigen presentation",

author = "Martin Rowe and Jianmin Zuo",

year = "2010",

month = mar,

day = "1",

doi = "10.1016/j.micinf.2009.12.001",

language = "English",

volume = "12",

pages = "173--181",

journal = "Microbes and Infection",

issn = "1769-714X",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

AU - Rowe, Martin

AU - Zuo, Jianmin

PY - 2010/3/1

Y1 - 2010/3/1

N2 - Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation

AB - Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation

KW - Immune-evasion

KW - Tumour virus

KW - Epstein-Barr virus

KW - Herpesvirus

KW - Immune response

KW - Antigen presentation

U2 - 10.1016/j.micinf.2009.12.001

DO - 10.1016/j.micinf.2009.12.001

M3 - Review article

C2 - 20004735

SN - 1769-714X

VL - 12

SP - 173

EP - 181

JO - Microbes and Infection

JF - Microbes and Infection

IS - 3

ER -

Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

Abstract

Keywords

Access to Document

Fingerprint

Cite this