Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?

Oliver J Pickles; Lennard Y W Lee; Thomas Starkey; Luke Freeman-Mills; Anna Olsson-Brown; Vinton Cheng; Daniel J Hughes; Alvin Lee; Karin Purshouse; Gary Middleton

doi:10.1038/s41416-020-0930-7

Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?

Oliver J Pickles
, Lennard Y W Lee
, Thomas Starkey
, Luke Freeman-Mills
, Anna Olsson-Brown
, Vinton Cheng
, Daniel J Hughes
, Alvin Lee
, Karin Purshouse
, Gary Middleton

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phenomenon, requiring careful real-world observation.

Original language	English
Pages (from-to)	691-693
Number of pages	3
Journal	British Journal of Cancer
Volume	123
Issue number	5
DOIs	https://doi.org/10.1038/s41416-020-0930-7
Publication status	Published - Sept 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1038/s41416-020-0930-7

Cite this

@article{0f7107c24e2348a38c75057daa6241de,

title = "Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?",

abstract = "The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phenomenon, requiring careful real-world observation.",

author = "Pickles, \{Oliver J\} and Lee, \{Lennard Y W\} and Thomas Starkey and Luke Freeman-Mills and Anna Olsson-Brown and Vinton Cheng and Hughes, \{Daniel J\} and Alvin Lee and Karin Purshouse and Gary Middleton",

year = "2020",

month = sep,

doi = "10.1038/s41416-020-0930-7",

language = "English",

volume = "123",

pages = "691--693",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Cancer Research UK",

number = "5",

}

TY - JOUR

T1 - Immune checkpoint blockade

T2 - releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?

AU - Pickles, Oliver J

AU - Lee, Lennard Y W

AU - Starkey, Thomas

AU - Freeman-Mills, Luke

AU - Olsson-Brown, Anna

AU - Cheng, Vinton

AU - Hughes, Daniel J

AU - Lee, Alvin

AU - Purshouse, Karin

AU - Middleton, Gary

PY - 2020/9

Y1 - 2020/9

N2 - The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phenomenon, requiring careful real-world observation.

AB - The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phenomenon, requiring careful real-world observation.

UR - https://www.scopus.com/pages/publications/85090045554

U2 - 10.1038/s41416-020-0930-7

DO - 10.1038/s41416-020-0930-7

M3 - Article

C2 - 32546835

SN - 0007-0920

VL - 123

SP - 691

EP - 693

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 5

ER -

Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this