Abstract
Ulcerative colitis (UC) is a relapsing and remitting disease characterised by chronic mucosal and submucosal inflammation of the colon and rectum. Treatment may vary depending upon the extent and severity of inflammation. Broadly speaking medical treatments aim to induce and then maintain remission. Surgery is indicated for inflammatory disease that is refractory to medical treatment or in cases of neoplastic transformation. Approximately 250% of patients with UC ultimately require colectomy. Ileal pouch-anal anastomosis (IPAA) has become the standard of care for patients with ulcerative colitis who ultimately require colectomy. This review will examine indications for IPAA, patient selection, technical aspects of surgery, management of complications and long term outcome following this procedure. (c) 2007 The WJG Press. All rights reserved.
Original language | English |
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Pages (from-to) | 3288-3300 |
Number of pages | 13 |
Journal | World Journal of Gastroenterology |
Volume | 13 |
Issue number | 24 |
Publication status | Published - 28 Jun 2007 |
Keywords
- ulcerative colitis
- ileal pouch anal anastomosis
- ileal pouch