Identifying men at ultra high risk of psychosis in a prison population

Manuela Jarrett*, Tom Craig, Janet Parrott, Andrew Forrester, Toby Winton-Brown, Helen Maguire, Philip McGuire, Lucia Valmaggia

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)

Abstract

Background: The prevalence of psychotic disorders among prisoners is relatively high. We sought to investigate the prevalence of men who have a very high risk of developing psychosis in a prison population. Methods: The Prodromal Questionnaire - Brief Version (Loewy, Pearson, Vinogradov, Bearden and Cannon, 2011), was used to screen newly-arrived prisoners in a London prison for features associated with an increased risk of psychosis. Concurrent validity was evaluated using the Comprehensive Assessment for At Risk Mental State (Yung et al., 2005). Results: 750 prisoners were screened and 301 were underwent further clinical assessment. 5% the total number of those screened met diagnostic criteria for the ARMS and 3% had recently developed a first episode of psychosis. Using endorsement of items that also caused distress, the PQ-B predicted an ARMS or a psychotic disorder with 90% sensitivity and 44% specificity. Conclusions: The PQ-B is effective in identifying people who are vulnerable to developing psychosis in a prison population.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalSchizophrenia Research
Volume136
Issue number1-3
DOIs
Publication statusPublished - Apr 2012

Bibliographical note

Funding Information:
The study was funded by a grant from the Guy's and St Thomas' Charitable Foundation (Ref number G080704). Guy's and St Thomas' had no further role in study design, collection, analysis and interpretation of data, in the writing of the report or to submit the final paper for publication.

Funding Information:
Our special thanks go to the staff and prisoners of the prison and the staff of OASIS. We would like to thank Dr Rachel Lowey for making the PQ available for the study. The project was financially supported by a generous grant from the Guy's and St. Thomas' Charitable Foundation . Dr Valmaggia is supported by a NARSAD Young Investigator Award and by a Peggy Pollack Research Fellowship from the Psychiatry Research Trust. We acknowledge the NIHR Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry Kings College London for their financial support.

Keywords

  • At risk mental state
  • Early detection
  • Prevalence
  • Prisoners

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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