Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans

Joanna E Cobb; Darren Plant; Edward Flynn; Meriem Tadjeddine; Philippe Dieudé; François Cornélis; Lisbeth Arlestig; Solbritt Rantapää Dahlqvist; George Goulielmos; Dimitrios T Boumpas; Prodromos Sidiropoulos; Sophine B Krintel; Lykke M Ornbjerg; Merete L Hetland; Lars Klareskog; Thomas Haeupl; Andrew Filer; Christopher D Buckley; Karim Raza; Torsten Witte; Reinhold E Schmidt; Oliver Fitzgerald; Douglas Veale; Stephen Eyre; Jane Worthington

doi:10.1371/journal.pone.0066456

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans

Joanna E Cobb, Darren Plant, Edward Flynn, Meriem Tadjeddine, Philippe Dieudé, François Cornélis, Lisbeth Arlestig, Solbritt Rantapää Dahlqvist, George Goulielmos, Dimitrios T Boumpas, Prodromos Sidiropoulos, Sophine B Krintel, Lykke M Ornbjerg, Merete L Hetland, Lars Klareskog, Thomas Haeupl, Andrew Filer, Christopher D Buckley, Karim Raza, Torsten WitteReinhold E Schmidt, Oliver Fitzgerald, Douglas Veale, Stephen Eyre, Jane Worthington

Immunology and Immunotherapy

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Abstract

Genome-wide association studies have facilitated the identification of over 30 susceptibility loci for rheumatoid arthritis (RA). However, evidence for a number of potential susceptibility genes have not so far reached genome-wide significance in studies of Caucasian RA.

Original language	English
Article number	e66456
Journal	PLoS ONE
Volume	8
Issue number	6
DOIs	https://doi.org/10.1371/journal.pone.0066456
Publication status	Published - 20 Jun 2013

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© 2013 Cobb et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Checked October 2015
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066456

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Cobb, J. E., Plant, D., Flynn, E., Tadjeddine, M., Dieudé, P., Cornélis, F., Arlestig, L., Dahlqvist, S. R., Goulielmos, G., Boumpas, D. T., Sidiropoulos, P., Krintel, S. B., Ornbjerg, L. M., Hetland, M. L., Klareskog, L., Haeupl, T., Filer, A., Buckley, C. D., Raza, K., ... Worthington, J. (2013). Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans. PLoS ONE, 8(6), Article e66456. https://doi.org/10.1371/journal.pone.0066456

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title = "Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans",

abstract = "Genome-wide association studies have facilitated the identification of over 30 susceptibility loci for rheumatoid arthritis (RA). However, evidence for a number of potential susceptibility genes have not so far reached genome-wide significance in studies of Caucasian RA.",

author = "Cobb, {Joanna E} and Darren Plant and Edward Flynn and Meriem Tadjeddine and Philippe Dieud{\'e} and Fran{\c c}ois Corn{\'e}lis and Lisbeth Arlestig and Dahlqvist, {Solbritt Rantap{\"a}{\"a}} and George Goulielmos and Boumpas, {Dimitrios T} and Prodromos Sidiropoulos and Krintel, {Sophine B} and Ornbjerg, {Lykke M} and Hetland, {Merete L} and Lars Klareskog and Thomas Haeupl and Andrew Filer and Buckley, {Christopher D} and Karim Raza and Torsten Witte and Schmidt, {Reinhold E} and Oliver Fitzgerald and Douglas Veale and Stephen Eyre and Jane Worthington",

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Cobb, JE, Plant, D, Flynn, E, Tadjeddine, M, Dieudé, P, Cornélis, F, Arlestig, L, Dahlqvist, SR, Goulielmos, G, Boumpas, DT, Sidiropoulos, P, Krintel, SB, Ornbjerg, LM, Hetland, ML, Klareskog, L, Haeupl, T, Filer, A, Buckley, CD, Raza, K, Witte, T, Schmidt, RE, Fitzgerald, O, Veale, D, Eyre, S & Worthington, J 2013, 'Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans', PLoS ONE, vol. 8, no. 6, e66456. https://doi.org/10.1371/journal.pone.0066456

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T1 - Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans

AU - Cobb, Joanna E

AU - Plant, Darren

AU - Flynn, Edward

AU - Tadjeddine, Meriem

AU - Dieudé, Philippe

AU - Cornélis, François

AU - Arlestig, Lisbeth

AU - Dahlqvist, Solbritt Rantapää

AU - Goulielmos, George

AU - Boumpas, Dimitrios T

AU - Sidiropoulos, Prodromos

AU - Krintel, Sophine B

AU - Ornbjerg, Lykke M

AU - Hetland, Merete L

AU - Klareskog, Lars

AU - Haeupl, Thomas

AU - Filer, Andrew

AU - Buckley, Christopher D

AU - Raza, Karim

AU - Witte, Torsten

AU - Schmidt, Reinhold E

AU - Fitzgerald, Oliver

AU - Veale, Douglas

AU - Eyre, Stephen

AU - Worthington, Jane

PY - 2013/6/20

Y1 - 2013/6/20

N2 - Genome-wide association studies have facilitated the identification of over 30 susceptibility loci for rheumatoid arthritis (RA). However, evidence for a number of potential susceptibility genes have not so far reached genome-wide significance in studies of Caucasian RA.

AB - Genome-wide association studies have facilitated the identification of over 30 susceptibility loci for rheumatoid arthritis (RA). However, evidence for a number of potential susceptibility genes have not so far reached genome-wide significance in studies of Caucasian RA.

U2 - 10.1371/journal.pone.0066456

DO - 10.1371/journal.pone.0066456

M3 - Article

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SN - 1932-6203

VL - 8

JO - PLoS ONE

JF - PLoS ONE

IS - 6

M1 - e66456

ER -

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in Europeans

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