Hypopituitarism: Clinical features, diagnosis, and management

Andrew Toogood, Paul Stewart

Research output: Contribution to journalArticle

56 Citations (Scopus)


Hypopituitarism is characterized by loss of function of the anterior pituitary gland. It is a rare condition that can present at any age and is caused by pathology of the hypothalamic-pituitary axis or one of many gene mutations. The symptoms and signs of hypopituitarism may evolve over several years and be nonspecific or related to the effects of the underlying disease process or to hormone deficiencies. Investigation of patients requires a combination of basal hormone levels and dynamic function tests; management requires regular monitoring. The goal of physicians managing patients who have hypopituitarism is to improve their health and long-term outcome.
Original languageEnglish
Pages (from-to)235-+
JournalEndocrinology and Metabolism Clinics of North America
Issue number1
Publication statusPublished - 1 Jan 2008


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