Hyperalgesia in the setting of anxiety: Sex differences and effects of the oestrous cycle in Wistar rats

Adam Devall; ZW Liu; Thelma Lovick

doi:10.1016/j.psyneuen.2008.10.021

Hyperalgesia in the setting of anxiety: Sex differences and effects of the oestrous cycle in Wistar rats

Adam Devall, ZW Liu, Thelma Lovick

Cancer and Genomic Sciences

Research output: Contribution to journal › Article

41 Citations (Scopus)

Abstract

Sex differences to noxious thermal cutaneous stimulation were compared in Wistar rats. Mate and female rats showed similar baseline tail flick latencies. However, sex differences emerged when nociceptive testing was carried out in the setting of mild non-noxious anxiogenic stress (4 Hz vibration for 5 min). On cessation of vibration stress 16/35 (46%) of mate rats showed hyperalgesia (decrease in tail flick latency tasting >20 min) whist the reminder showed a brief (

Original language	English
Pages (from-to)	587-596
Number of pages	10
Journal	Psychoneuroendocrinology
Volume	34
Issue number	4
DOIs	https://doi.org/10.1016/j.psyneuen.2008.10.021
Publication status	Published - 1 May 2009

Keywords

Rat
Tail flick reflex
Progesterone withdrawal
Anxiety
Stress-induced hyperalgesia
Oestrous cycle

Access to Document

10.1016/j.psyneuen.2008.10.021

Cite this

@article{e048e510ed0b439580b6657ab9a7b631,

title = "Hyperalgesia in the setting of anxiety: Sex differences and effects of the oestrous cycle in Wistar rats",

abstract = "Sex differences to noxious thermal cutaneous stimulation were compared in Wistar rats. Mate and female rats showed similar baseline tail flick latencies. However, sex differences emerged when nociceptive testing was carried out in the setting of mild non-noxious anxiogenic stress (4 Hz vibration for 5 min). On cessation of vibration stress 16/35 (46%) of mate rats showed hyperalgesia (decrease in tail flick latency tasting >20 min) whist the reminder showed a brief (",

keywords = "Rat, Tail flick reflex, Progesterone withdrawal, Anxiety, Stress-induced hyperalgesia, Oestrous cycle",

author = "Adam Devall and ZW Liu and Thelma Lovick",

year = "2009",

month = may,

day = "1",

doi = "10.1016/j.psyneuen.2008.10.021",

language = "English",

volume = "34",

pages = "587--596",

journal = "Psychoneuroendocrinology",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Hyperalgesia in the setting of anxiety: Sex differences and effects of the oestrous cycle in Wistar rats

AU - Devall, Adam

AU - Liu, ZW

AU - Lovick, Thelma

PY - 2009/5/1

Y1 - 2009/5/1

N2 - Sex differences to noxious thermal cutaneous stimulation were compared in Wistar rats. Mate and female rats showed similar baseline tail flick latencies. However, sex differences emerged when nociceptive testing was carried out in the setting of mild non-noxious anxiogenic stress (4 Hz vibration for 5 min). On cessation of vibration stress 16/35 (46%) of mate rats showed hyperalgesia (decrease in tail flick latency tasting >20 min) whist the reminder showed a brief (

AB - Sex differences to noxious thermal cutaneous stimulation were compared in Wistar rats. Mate and female rats showed similar baseline tail flick latencies. However, sex differences emerged when nociceptive testing was carried out in the setting of mild non-noxious anxiogenic stress (4 Hz vibration for 5 min). On cessation of vibration stress 16/35 (46%) of mate rats showed hyperalgesia (decrease in tail flick latency tasting >20 min) whist the reminder showed a brief (

KW - Rat

KW - Tail flick reflex

KW - Progesterone withdrawal

KW - Anxiety

KW - Stress-induced hyperalgesia

KW - Oestrous cycle

U2 - 10.1016/j.psyneuen.2008.10.021

DO - 10.1016/j.psyneuen.2008.10.021

M3 - Article

C2 - 19059728

VL - 34

SP - 587

EP - 596

JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

IS - 4

ER -

Hyperalgesia in the setting of anxiety: Sex differences and effects of the oestrous cycle in Wistar rats

Abstract

Keywords

Access to Document

Fingerprint

Cite this