Hydrogen bond regulated platelet micelles by crystallization-driven self-assembly and templated growth for poly(ε-caprolactone) block copolymers

Yawei Su, Yikun Jiang, Liping Liu, Yujie Xie, Shichang Chen, Yongjun Wang, Rachel O'Reilly, Zaizai Tong

Research output: Contribution to journalArticlepeer-review

Abstract

Living crystallization-driven self-assembly (CDSA) is a powerful approach to tailor nanoparticles with controlled size and spatially defined compositions from amphiphilic crystalline block copolymers (BCPs). However, a variety of external constraints usually make the successful applications of living CDSA difficult. Herein, such constraints arising from strong hydrogen-bond (H-bond) interactions between unimers that lead to the failure of living CDSA are effectively overcome via reduction of the H-bond strength. In particular, by adding a H-bond disruptor trifluoroethanol (TFE), decreasing the unimer concentration, and reducing the corona segment length, the H-bond strength between unimers could be efficiently alleviated, leading to the formation of uniform two-dimensional (2D) platelets with controlled size and block comicelles with spatially defined corona chemistries. Moreover, by selectively anchoring one-dimensional (1D) seeds on the surface of as-prepared 2D block comicelles through H-bond interaction, the epitaxial growth of a crystalline BCP from immobilized 1D seeds on 2D platelets illustrates competitive growth behavior in a spatially confined environment.
Original languageEnglish
Pages (from-to)1067-1076
Number of pages10
JournalMacromolecules
Volume55
Issue number3
Early online date25 Jan 2022
DOIs
Publication statusPublished - 8 Feb 2022

Keywords

  • H-bond
  • CDSA
  • unimers

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