Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium

C Feldman, R Cockeran, M J Jedrzejas, T J Mitchell, R Anderson

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


The main objective of this study was to investigate the effects of pneumococcal hyaluronidase (0.1-10microg/ml), alone and in combination with pneumolysin (50 and 100ng/ml), on human ciliated epithelium.
Original languageEnglish
Pages (from-to)11-5
Number of pages5
JournalInternational Journal of Infectious Diseases
Issue number1
Publication statusPublished - Jan 2007


  • Bacterial Proteins
  • Calcium
  • Cilia
  • Dose-Response Relationship, Drug
  • Drug Synergism
  • Epithelium
  • Erythrocytes
  • Humans
  • Hyaluronoglucosaminidase
  • Neutrophils
  • Streptolysins


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