TY - JOUR
T1 - Human metapneumovius in a haematopoietic stem cell recipient with fatal lower respiratory tract disease
AU - Cane, Patricia
AU - van den Hoogen, BG
AU - Chakrabarti, S
AU - Fegan, CD
AU - Osterhaus, ADME
PY - 2003/2/1
Y1 - 2003/2/1
N2 - Respiratory viruses are increasingly recognized as a cause of pneumonitis following haematopoietic stem cell transplantation (HSCT). However, frequently, no pathogen is identified in cases of suspected viral pneumonia. Recently, a previously undescribed paramyxovirus, designated 'human metapneumovirus' (hMPV), was isolated from children with respiratory illness. We have detected hMPV as the sole pathogen in the nasopharyngeal aspirate of an HSCT recipient who succumbed to progressive respiratory failure following an upper respiratory prodrome. This report highlights the importance of further studies to elucidate the role of hMPV in causing respiratory illnesses in the HSCT population.
AB - Respiratory viruses are increasingly recognized as a cause of pneumonitis following haematopoietic stem cell transplantation (HSCT). However, frequently, no pathogen is identified in cases of suspected viral pneumonia. Recently, a previously undescribed paramyxovirus, designated 'human metapneumovirus' (hMPV), was isolated from children with respiratory illness. We have detected hMPV as the sole pathogen in the nasopharyngeal aspirate of an HSCT recipient who succumbed to progressive respiratory failure following an upper respiratory prodrome. This report highlights the importance of further studies to elucidate the role of hMPV in causing respiratory illnesses in the HSCT population.
KW - stem cell transplant
KW - human metapneumovirus
UR - http://www.scopus.com/inward/record.url?scp=0037297954&partnerID=8YFLogxK
U2 - 10.1038/sj.bmt.1703849
DO - 10.1038/sj.bmt.1703849
M3 - Article
C2 - 12621469
SN - 0268-3369
VL - 31
SP - 309
EP - 310
JO - Bone Marrow Transplantation
JF - Bone Marrow Transplantation
IS - 4
ER -
