High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells

Nicola J Rogers; Sunil Claire; Robert M Harris; Shiva Farabi; Gerald Zikeli; Iain B Styles; Nikolas J Hodges; Zoe Pikramenou

doi:10.1039/c3cc47606e

High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells

Nicola J Rogers, Sunil Claire, Robert M Harris, Shiva Farabi, Gerald Zikeli, Iain B Styles, Nikolas J Hodges, Zoe Pikramenou

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.

Original language	English
Pages (from-to)	617-9
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	5
Early online date	5 Nov 2013
DOIs	https://doi.org/10.1039/c3cc47606e
Publication status	Published - 18 Jan 2014

Keywords

Cell Line, Tumor
Coordination Complexes
Gold
Humans
Metal Nanoparticles
Microscopy, Confocal
Particle Size
Ruthenium

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1039/c3cc47606eLicence: None: All rights reserved

Cite this

@article{184c7bf5fe72456d8f5b1a68dfa00fd3,

title = "High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells",

abstract = "Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.",

keywords = "Cell Line, Tumor, Coordination Complexes, Gold, Humans, Metal Nanoparticles, Microscopy, Confocal, Particle Size, Ruthenium",

author = "Rogers, {Nicola J} and Sunil Claire and Harris, {Robert M} and Shiva Farabi and Gerald Zikeli and Styles, {Iain B} and Hodges, {Nikolas J} and Zoe Pikramenou",

year = "2014",

month = jan,

day = "18",

doi = "10.1039/c3cc47606e",

language = "English",

volume = "50",

pages = "617--9",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "5",

}

TY - JOUR

T1 - High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells

AU - Rogers, Nicola J

AU - Claire, Sunil

AU - Harris, Robert M

AU - Farabi, Shiva

AU - Zikeli, Gerald

AU - Styles, Iain B

AU - Hodges, Nikolas J

AU - Pikramenou, Zoe

PY - 2014/1/18

Y1 - 2014/1/18

N2 - Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.

AB - Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.

KW - Cell Line, Tumor

KW - Coordination Complexes

KW - Gold

KW - Humans

KW - Metal Nanoparticles

KW - Microscopy, Confocal

KW - Particle Size

KW - Ruthenium

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84890326690&partnerID=MN8TOARS

U2 - 10.1039/c3cc47606e

DO - 10.1039/c3cc47606e

M3 - Article

C2 - 24281162

SN - 1359-7345

VL - 50

SP - 617

EP - 619

JO - Chemical Communications

JF - Chemical Communications

IS - 5

ER -

High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this