Abstract
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections have a devastating effect on patients receiving hemodialysis. To what extent infection-induced antibody responses are maintained, or protective, is unknown. This study describes the evolution of antibodies against the SARS-CoV-2 spike protein in a cohort of 990 patients on hemodialysis. During the first wave of the pandemic, 26% of patients had developed antispike SARS-CoV-2 antibodies. Fewer PCR-confirmed second-wave infections were observed in patients with pre-existing antibodies (4.2%) than those without antibodies (11.4%). This study shows that SARS-CoV-2 antibodies in patients on hemodialysis are well maintained and associate with reduced risk of subsequent SARS-CoV-2 infection.
Original language | English |
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Pages (from-to) | 2140-2142 |
Number of pages | 3 |
Journal | Journal of the American Society of Nephrology |
Volume | 32 |
Issue number | 9 |
Early online date | 2 Aug 2021 |
DOIs | |
Publication status | Published - Sept 2021 |
Keywords
- Antibody
- COVID-19
- Haemodialysis
- SARS-CoV-2