Geometric description for the anatomy of the mitral valve: a review

Diana Cruz De Oliveira, Janaki Srinivasan, Daniel Espino, Keith Buchan, Dana Dawson, Duncan Shepherd

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)
100 Downloads (Pure)


The mitral valve is a complex anatomical structure whose physiological functioning relies on the biomechanical properties and structural integrity of its components. Their compromise can lead to mitral valve dysfunction, associated with morbidity and mortality. Therefore, a review on the morphometry of the mitral valve is crucial, more specifically on the importance of valve dimensions and shape for its function. This review initially provides a brief background on the anatomy and physiology of the mitral valve, followed by an analysis of the morphological information available. A characterisation of mathematical descriptions of several parts of the valve is performed and the impact of different dimensions and shape changes in disease is then outlined. Finally, a section regarding future directions and recommendations for the use of morphometric information in clinical analysis of the mitral valve is presented.

Original languageEnglish
Pages (from-to)209-224
JournalJournal of Anatomy
Issue number2
Early online date3 Apr 2020
Publication statusE-pub ahead of print - 3 Apr 2020


  • biomechanics
  • computational anatomy
  • mitral valve
  • mitral valve disease
  • morphology analysis

ASJC Scopus subject areas

  • Anatomy
  • Ecology, Evolution, Behavior and Systematics
  • Histology
  • Molecular Biology
  • Developmental Biology
  • Cell Biology


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