Geographical structure of the Y-chromosomal genetic landscape of the levant: A coastal-inland contrast

Mirvat El-Sibai, Daniel E. Platt, Marc Haber, Yali Xue, Sonia C. Youhanna, R. Spencer Wells, Hassan Izaabel, May F. Sanyoura, Haidar Harmanani, Maziar Ashrafian Bonab, Jaafar Behbehani, Fuad Hashwa, Chris Tyler-Smith, Pierre A. Zalloua

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

We have examined the male-specific phylogeography of the Levant and its surroundings by analyzing Y-chromosomal haplogroup distributions using 5874 samples (885 new) from 23 countries. The diversity within some of these haplogroups was also examined. The Levantine populations showed clustering in SNP and STR analyses when considered against a broad Middle-East and North African background. However, we also found a coastal-inland, east-west pattern of diversity and frequency distribution in several haplogroups within the small region of the Levant. Since estimates of effective population size are similar in the two regions, this strong pattern is likely to have arisen mainly from differential migrations, with different lineages introduced from the east and west.

Original languageEnglish
Pages (from-to)568-581
Number of pages14
JournalAnnals of Human Genetics
Volume73
Issue number6
DOIs
Publication statusPublished - Nov 2009

Keywords

  • Levant
  • Y chromosome
  • Y-SNP
  • Y-STR

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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