Abstract
Programmed cell death, or apoptosis, is a highly conserved cellular process that has been intensively investigated in nematodes, flies and mammals. The genetic conservation, the low redundancy, the feasibility for high-throughput genetic screens and the identification of temporally and spatially regulated apoptotic responses make Drosophila melanogaster a great model for the study of apoptosis. Here, we review the key players of the cell death pathway in Drosophila and discuss their roles in apoptotic and non-apoptotic processes.
| Original language | English |
|---|---|
| Pages (from-to) | 78-90 |
| Number of pages | 13 |
| Journal | Fly |
| Volume | 3 |
| Issue number | 1 |
| Publication status | Published - 2009 |