TY - CHAP
T1 - Gene expression analyses for elucidating mechanisms of hormonal action in plants
AU - Bassel, G.W.
AU - Provart, N.J.
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Analysis of large-scale gene expression data sets is proving to be a powerful tool for gene function prediction, cis-element discovery and hypothesis generation using Arabidopsis thaliana. Public initiatives led by the AtGenExpress Consortium and experiments conducted by individual researchers to document the transcriptome of Arabidopsis thaliana have led to a large numbers of data sets being made publicly available for data mining by so-called "electronic northerns", co-expression analysis and other means. Given that approximately 50% genes in Arabidopsis have no function ascribed to them by "traditional" homology searches, and that only around 10% of the genes have had their function confirmed in the laboratory, these analyses can accelerate the identification of potential gene function with a mouse-click. This chapter covers the use of data mining tools available at the Bio-Array Resource ( www.bar.utoronto.ca) for hypothesis generation in the context of plant hormone biology.
AB - Analysis of large-scale gene expression data sets is proving to be a powerful tool for gene function prediction, cis-element discovery and hypothesis generation using Arabidopsis thaliana. Public initiatives led by the AtGenExpress Consortium and experiments conducted by individual researchers to document the transcriptome of Arabidopsis thaliana have led to a large numbers of data sets being made publicly available for data mining by so-called "electronic northerns", co-expression analysis and other means. Given that approximately 50% genes in Arabidopsis have no function ascribed to them by "traditional" homology searches, and that only around 10% of the genes have had their function confirmed in the laboratory, these analyses can accelerate the identification of potential gene function with a mouse-click. This chapter covers the use of data mining tools available at the Bio-Array Resource ( www.bar.utoronto.ca) for hypothesis generation in the context of plant hormone biology.
UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-60349118100&md5=eca6751c761f929281187c85c5601eac
U2 - 10.1007/978-1-59745-477-3-3
DO - 10.1007/978-1-59745-477-3-3
M3 - Chapter
AN - SCOPUS:60349118100
SN - 9781934115329
VL - 495
SP - 21
EP - 37
BT - Methods in Molecular Biology
ER -