Gamma(delta) T cells: non-classical ligands for non-classical cells

C R Steele, D E Oppenheim, A C Hayday

Research output: Contribution to journalArticle

35 Citations (Scopus)


A recent study describes direct binding between a gammadelta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alphabeta T cells.

Original languageEnglish
Pages (from-to)R282-5
JournalCurrent Biology
Issue number7
Publication statusPublished - 6 Apr 2000


  • Crystallography
  • Histocompatibility Antigens Class I
  • Models, Immunological
  • Models, Molecular
  • Proteins
  • Receptors, Antigen, T-Cell, gamma-delta
  • T-Lymphocyte Subsets


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