Further developments towards a genome-scale metabolic model of yeast

Paul D Dobson, Kieran Smallbone, Daniel Jameson, Evangelos Simeonidis, Karin Lanthaler, Pınar Pir, Chuan Lu, Neil Swainston, Warwick B Dunn, Paul Fisher, Duncan Hull, Marie Brown, Olusegun Oshota, Natalie J Stanford, Douglas B Kell, Ross D King, Stephen G Oliver, Robert D Stevens, Pedro Mendes

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)


To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, while rigorously evidenced and well annotated, under-represented metabolite transport, lipid metabolism and other pathways, and was not amenable to constraint-based analyses because of lack of pathway connectivity.
Original languageEnglish
Pages (from-to)145
JournalBMC systems biology
Publication statusPublished - 2010


Dive into the research topics of 'Further developments towards a genome-scale metabolic model of yeast'. Together they form a unique fingerprint.

Cite this