Keyphrases
Smooth muscle Cells
100%
Fluorinated
100%
Perhexiline
100%
Pulmonary Arterial Hypertension
100%
Vascular Proliferation
100%
Pulmonary Artery Smooth muscle Cells (PASMCs)
66%
Pulmonary Hypertension
44%
Pyruvate Dehydrogenase
44%
Cell Proliferation
22%
Pharmacokinetics
22%
Cytochrome P450 2D6 (CYP2D6)
22%
Warburg Effect
22%
Pyruvate Dehydrogenase Activity
22%
Glycolysis
11%
Concentration-dependent
11%
Apoptosis
11%
Phosphorylation
11%
Induced Apoptosis
11%
Therapeutic Agents
11%
Oxidative Phosphorylation (OXPHOS)
11%
Carnitine Palmitoyltransferase 1A (CPT1A)
11%
ERK Pathway
11%
Cardiac Disease
11%
Adjusted Dose
11%
Poor Metabolizer
11%
Mitochondrial Respiration
11%
Polymorphic Variation
11%
Blood Levels
11%
Aerobic Glycolysis
11%
Dephosphorylation
11%
Hepatotoxicity
11%
Caspase 3/7 Activity
11%
Warburg
11%
ERK1
11%
Seahorse Analysis
11%
Fluorinated Derivatives
11%
Pulmonary Artery Smooth muscle Cell Proliferation
11%
Pharmacology, Toxicology and Pharmaceutical Science
Pulmonary Hypertension
100%
Perhexiline
100%
Pyruvate Dehydrogenase
66%
Pharmacokinetics
22%
CYP2D6
22%
Carnitine Palmitoyltransferase I
11%
Caspase 3
11%
Heart Disease
11%
Hepatotoxicity
11%
Mitogen Activated Protein Kinase 3
11%
Seahorse
11%