Fetal lower urinary tract obstruction

    Research output: Contribution to journalArticle

    70 Citations (Scopus)


    Fetal lower urinary tract obstruction affects 2.2 per 10,000 births. It is a consequence of a range of pathological processes, most commonly posterior urethral valves (64%) or urethral atresia (39%). It is a condition of high mortality and morbidity associated with progressive renal dysfunction and oligohydramnios, and hence fetal pulmonary hypoplasia. Accurate detection is possible via ultrasound, but the underlying pathology is often unknown. In future, magnetic resonance imaging (MRI) may be increasingly used alongside ultrasound in the diagnosis and assessment of fetuses with lower urinary tract obstruction. Fetal urine analysis may provide improvements in prenatal determination of renal prognosis, but the optimum criteria to be used remain unclear. It is now possible to decompress the obstruction in utero via percutaneous vesico-amniotic shunting or cystoscopic techniques. In appropriately selected fetuses intervention may improve perinatal survival, but long-term renal morbidity amongst survivors remains problematic.
    Original languageEnglish
    Pages (from-to)464-70
    Number of pages7
    JournalSeminars in Fetal & Neonatal Medicine
    Publication statusPublished - 1 Jan 2007


    • posterior urethral valves
    • lower urinary tract obstruction
    • vesico-amniotic shunting


    Dive into the research topics of 'Fetal lower urinary tract obstruction'. Together they form a unique fingerprint.

    Cite this