Abstract
Fecal microbiota transplantation (FMT) is the infusion of feces from a healthy donor into the gut of a recipient to treat a dysbiosis-related disease. FMT has been proven to be a safe and effective treatment for Clostridioides difficile infection, but increasing evidence supports the role of FMT in other gastrointestinal and extraintestinal diseases. The aim of this review is to paint the landscape of current evidence of FMT in different fields of application (including irritable bowel syndrome, inflammatory bowel disease, liver disorders, decolonization of multidrug-resistant bacteria, metabolic disorders and neurological disorders), as well as to discuss the current regulatory scenario of FMT, and hypothesize future directions of FMT.
Original language | English |
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Pages (from-to) | 1173-1186 |
Number of pages | 14 |
Journal | Future Microbiology |
Volume | 15 |
Issue number | 12 |
DOIs | |
Publication status | Published - Aug 2020 |
Bibliographical note
Publisher Copyright:© 2020 Future Medicine Ltd.. All rights reserved.
Keywords
- Clostridium difficile
- cancer
- fecal microbiota transplantation
- inflammatory bowel disease
- irritable bowel syndrome
- metabolic syndrome
- microbiome
- microbiota
ASJC Scopus subject areas
- Microbiology
- Microbiology (medical)