Abstract
Preoperative (neoadjuvant) chemotherapy and radiotherapy are more effective than similar postoperative treatment for oesophageal, gastric, and rectal cancers, perhaps because of more effective micrometastasis eradication and reduced risk of incomplete excision and tumour cell shedding during surgery. The FOxTROT trial aims to investigate the feasibility, safety, and efficacy of preoperative chemotherapy for colon cancer.
Original language | English |
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Pages (from-to) | 1152-60 |
Number of pages | 9 |
Journal | The Lancet Oncology |
Volume | 13 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2012 |
Bibliographical note
Copyright © 2012 Elsevier Ltd. All rights reserved.Keywords
- Neoplasm Staging
- Rectal Neoplasms
- Combined Modality Therapy
- Humans
- Neoadjuvant Therapy
- Aged
- Antibodies, Monoclonal
- Aged, 80 and over
- Fluorouracil
- Adult
- Antineoplastic Combined Chemotherapy Protocols
- Organoplatinum Compounds
- Middle Aged
- Preoperative Period
- Colonic Neoplasms
- Female
- Male