Family resemblances? Ligand binding and activation of family A and B G-protein-coupled receptors

DR Poyner, Mark Wheatley

Research output: Contribution to journalArticle

Abstract

In April 2007, the Biochemical Society held a meeting to compare and contrast ligand binding and activation of Family A and B GPCRs (G-protein-coupled receptors). Being the largest class, Family A GPCRs usually receive the most attention, although a previous Biochemical Society meeting has focused on Family B GPCRs. The aim of the present meeting was to bring researchers of both families together in order to identify commonalities between the two. The present article introduces the proceedings of the meeting, briefly commenting on the focus of each of the following articles.
Original languageEnglish
Pages (from-to)707-8
Number of pages2
JournalBiochemical Society Transactions
Volume35
Issue numberPt 4
DOIs
Publication statusPublished - 1 Aug 2007

Keywords

  • ligand binding
  • G-protein-coupled receptor (GPCR)
  • receptor activation
  • molecular modelling
  • drug design

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