Factors associated with chronic depressive symptoms across adolescence and young adulthood: a UK birth cohort study

B B Durdurak; B Williams; A Zhigalov; A Moore; P Mallikarjun; D Wong; S Marwaha; I Morales-Muñoz

doi:10.1017/S2045796024000350

Factors associated with chronic depressive symptoms across adolescence and young adulthood: a UK birth cohort study

B B Durdurak^*, B Williams, A Zhigalov, A Moore, P Mallikarjun, D Wong, S Marwaha, I Morales-Muñoz

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

AIMS: Identifying children and/or adolescents who are at highest risk for developing chronic depression is of utmost importance, so that we can develop more effective and targeted interventions to attenuate the risk trajectory of depression. To address this, the objective of this study was to identify young people with persistent depressive symptoms across adolescence and young adulthood and examine the prospective associations between factors and persistent depressive symptoms in young people.

METHODS: We used data from 6711 participants in the Avon Longitudinal Study of Parents and Children. Depressive symptoms were assessed at 12.5, 13.5, 16, 17.5, 21 and 22 years with the Short Mood and Feelings Questionnaire, and we further examined the influence of multiple biological, psychological and social factors in explaining chronic depressive symptoms.

RESULTS: Using latent class growth analysis, we identified four trajectories of depressive symptoms: persistent high, persistent low, persistent moderate and increasing high. After applying several logistic regression models, we found that loneliness and feeling less connected at school were the most relevant factors for chronic course of depressive symptoms.

CONCLUSIONS: Our findings contribute with the identification of those children who are at highest risk for developing chronic depressive symptoms.

Original language	English
Article number	e32
Journal	Epidemiology and Psychiatric Sciences
Volume	33
DOIs	https://doi.org/10.1017/S2045796024000350
Publication status	Published - 26 Jun 2024

Keywords

Humans
Adolescent
Depression/psychology
United Kingdom/epidemiology
Male
Female
Young Adult
Longitudinal Studies
Chronic Disease/psychology
Risk Factors
Child
Loneliness/psychology
Surveys and Questionnaires
Cohort Studies
Adult
Prospective Studies

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10.1017/S2045796024000350Licence: Creative Commons: Attribution (CC BY)

DurdurakBB2024FactorsFinal published version, 451 KBLicence: Creative Commons: Attribution (CC BY)

Prevention of persistent high levels of depression across adolescence and young adulthood: the role of active ingredients [Wellcome Mental Health Data Prize]
Zhigalov, A., Mallikarjun, P., Morales-Munoz, I. & Marwaha, S.
THE WELLCOME TRUST
22/08/22 → 21/02/23
Project: Research

Cite this

@article{e7955e9a25224cb7b6a90b8dc9a57ef8,

title = "Factors associated with chronic depressive symptoms across adolescence and young adulthood: a UK birth cohort study",

abstract = "AIMS: Identifying children and/or adolescents who are at highest risk for developing chronic depression is of utmost importance, so that we can develop more effective and targeted interventions to attenuate the risk trajectory of depression. To address this, the objective of this study was to identify young people with persistent depressive symptoms across adolescence and young adulthood and examine the prospective associations between factors and persistent depressive symptoms in young people.METHODS: We used data from 6711 participants in the Avon Longitudinal Study of Parents and Children. Depressive symptoms were assessed at 12.5, 13.5, 16, 17.5, 21 and 22 years with the Short Mood and Feelings Questionnaire, and we further examined the influence of multiple biological, psychological and social factors in explaining chronic depressive symptoms.RESULTS: Using latent class growth analysis, we identified four trajectories of depressive symptoms: persistent high, persistent low, persistent moderate and increasing high. After applying several logistic regression models, we found that loneliness and feeling less connected at school were the most relevant factors for chronic course of depressive symptoms.CONCLUSIONS: Our findings contribute with the identification of those children who are at highest risk for developing chronic depressive symptoms.",

keywords = "Humans, Adolescent, Depression/psychology, United Kingdom/epidemiology, Male, Female, Young Adult, Longitudinal Studies, Chronic Disease/psychology, Risk Factors, Child, Loneliness/psychology, Surveys and Questionnaires, Cohort Studies, Adult, Prospective Studies",

author = "Durdurak, {B B} and B Williams and A Zhigalov and A Moore and P Mallikarjun and D Wong and S Marwaha and I Morales-Mu{\~n}oz",

year = "2024",

month = jun,

day = "26",

doi = "10.1017/S2045796024000350",

language = "English",

volume = "33",

journal = "Epidemiology and Psychiatric Sciences",

issn = "2045-7960",

publisher = "Cambridge University Press",

}

TY - JOUR

T1 - Factors associated with chronic depressive symptoms across adolescence and young adulthood

T2 - a UK birth cohort study

AU - Durdurak, B B

AU - Williams, B

AU - Zhigalov, A

AU - Moore, A

AU - Mallikarjun, P

AU - Wong, D

AU - Marwaha, S

AU - Morales-Muñoz, I

PY - 2024/6/26

Y1 - 2024/6/26

N2 - AIMS: Identifying children and/or adolescents who are at highest risk for developing chronic depression is of utmost importance, so that we can develop more effective and targeted interventions to attenuate the risk trajectory of depression. To address this, the objective of this study was to identify young people with persistent depressive symptoms across adolescence and young adulthood and examine the prospective associations between factors and persistent depressive symptoms in young people.METHODS: We used data from 6711 participants in the Avon Longitudinal Study of Parents and Children. Depressive symptoms were assessed at 12.5, 13.5, 16, 17.5, 21 and 22 years with the Short Mood and Feelings Questionnaire, and we further examined the influence of multiple biological, psychological and social factors in explaining chronic depressive symptoms.RESULTS: Using latent class growth analysis, we identified four trajectories of depressive symptoms: persistent high, persistent low, persistent moderate and increasing high. After applying several logistic regression models, we found that loneliness and feeling less connected at school were the most relevant factors for chronic course of depressive symptoms.CONCLUSIONS: Our findings contribute with the identification of those children who are at highest risk for developing chronic depressive symptoms.

AB - AIMS: Identifying children and/or adolescents who are at highest risk for developing chronic depression is of utmost importance, so that we can develop more effective and targeted interventions to attenuate the risk trajectory of depression. To address this, the objective of this study was to identify young people with persistent depressive symptoms across adolescence and young adulthood and examine the prospective associations between factors and persistent depressive symptoms in young people.METHODS: We used data from 6711 participants in the Avon Longitudinal Study of Parents and Children. Depressive symptoms were assessed at 12.5, 13.5, 16, 17.5, 21 and 22 years with the Short Mood and Feelings Questionnaire, and we further examined the influence of multiple biological, psychological and social factors in explaining chronic depressive symptoms.RESULTS: Using latent class growth analysis, we identified four trajectories of depressive symptoms: persistent high, persistent low, persistent moderate and increasing high. After applying several logistic regression models, we found that loneliness and feeling less connected at school were the most relevant factors for chronic course of depressive symptoms.CONCLUSIONS: Our findings contribute with the identification of those children who are at highest risk for developing chronic depressive symptoms.

KW - Humans

KW - Adolescent

KW - Depression/psychology

KW - United Kingdom/epidemiology

KW - Male

KW - Female

KW - Young Adult

KW - Longitudinal Studies

KW - Chronic Disease/psychology

KW - Risk Factors

KW - Child

KW - Loneliness/psychology

KW - Surveys and Questionnaires

KW - Cohort Studies

KW - Adult

KW - Prospective Studies

U2 - 10.1017/S2045796024000350

DO - 10.1017/S2045796024000350

M3 - Article

C2 - 38920396

SN - 2045-7960

VL - 33

JO - Epidemiology and Psychiatric Sciences

JF - Epidemiology and Psychiatric Sciences

M1 - e32

ER -

Factors associated with chronic depressive symptoms across adolescence and young adulthood: a UK birth cohort study

Abstract

Keywords

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Prevention of persistent high levels of depression across adolescence and young adulthood: the role of active ingredients [Wellcome Mental Health Data Prize]

Cite this