Extended semen examinations in the sixth edition of the World Health Organization manual on semen analysis: contributing to the understanding of the function of the male reproductive system

Elisabetta Baldi, Meurig Thomas Gallagher, Stepan Krasnyak, Jackson Kirkman-Brown, Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen

Research output: Contribution to journalReview articlepeer-review

Abstract

In the sixth edition of the World Health Organization manual for the examination and processing of human semen, extended examina- tion methods to provide key diagnostics in the investigation of the male reproductive system function are elaborated. These go beyond the basic analysis of semen and may be useful in more specifically guiding the clinical characterization of fertile or infertile men. Among the extended examinations included in the chapter, the use of multiparametric scoring for sperm morphological defects, sperm DNA frag- mentation, and the roles for computer-assisted analysis of sperm or semen are arguably those that will be the most widely used and may also cause the most debate.
Original languageEnglish
JournalFertility and Sterility
Early online date3 Jan 2022
DOIs
Publication statusE-pub ahead of print - 3 Jan 2022

Keywords

  • fertility
  • infertility
  • world health organisation
  • semen analysis
  • male reproduction
  • CASA
  • sperm motility
  • sperm DNA
  • Multiparametric

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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