Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system

Elisabetta Baldi, Meurig Thomas Gallagher, Stepan Krasnyak, Jackson Kirkman-Brown, Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen

Research output: Contribution to journalReview articlepeer-review

Abstract

In the sixth edition of the World Health Organization manual for the examination and processing of human semen, extended examination methods to provide key diagnostics in the investigation of the male reproductive system function are elaborated. These go beyond the basic analysis of semen and may be useful in more specifically guiding the clinical characterization of fertile or infertile men. Among the extended examinations included in the chapter, the use of multiparametric scoring for sperm morphological defects, sperm DNA fragmentation, and the roles for computer-assisted analysis of sperm or semen are arguably those that will be the most widely used and may also cause the most debate.
Original languageEnglish
Pages (from-to)252-257
Number of pages6
JournalFertility and Sterility
Volume117
Issue number2
Early online date3 Jan 2022
DOIs
Publication statusPublished - 1 Mar 2022

Bibliographical note

Funding Information:
The development of the “sixth edition of World Health Organization (WHO) laboratory manual for the examination and processing of human semen” was funded by the UNDP-UNFPA-UNICEF-WHO-World Bank Special Programme of Research, Development and Research Training in Human Reproduction, a cosponsored programme executed by WHO.

Keywords

  • fertility
  • infertility
  • world health organisation
  • semen analysis
  • male reproduction
  • CASA
  • sperm motility
  • sperm DNA
  • Multiparametric

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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