Exposure assessment: Recommendations for nanotechnology-based pesticides

D. Stone, B.J. Harper, S.L. Harper, I. Lynch, K. Dawson

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Given the development of nanotechnology within numerous scientific disciplines, it is likely that nanoscale products have been and will be used for agricultural, vector, and urban pest control prior to a complete evaluation of exposure and risk. Significant differences may exist between nanotechnology-based pesticides (NBPs) and conventional pesticides, primarily due to size and surface characteristics. These differences may result in changes in bioavailability, sensitivity, dosimetry, and pharmacokinetics. This paper considers the role of exposure assessment in the regulation of NBPs. While the existing regulatory infrastructure for pesticides is well established, several issues specific to NBP exposure are discussed, including: (1) disclosures of nanoparticle characteristics in product formulations; (2) additional uncertainty factors for NBPs with inadequate data; (3) route-specific approaches for assessing exposure; (4) testing with the commercial form of NBPs; (5) initiation of a health surveillance program; and (6) development of educational programs.
Original languageEnglish
Pages (from-to)467-474
Number of pages8
JournalInternational Journal of Occupational Medicine and Environmental Health
Issue number4
Publication statusPublished - 1 Jan 2010

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Copyright 2010 Elsevier B.V., All rights reserved.


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