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Exploring roll compaction of two commonly used pharmaceutical powders

  • Shen Yu
  • , B Gururajan
  • , G Reynolds
  • , R Roberts
  • , Chuan-yu Wu
  • , Michael Adams

Research output: Contribution to journalArticle

Abstract

The effect of powder flow properties on roll compaction behaviour of microcrystalline cellulose (MCC) and di-calcium phosphate dihydrate (DCPD), which have distinctive flow properties, was experimentally investigated. A robust approach for determining the nip angle that defines the compaction region was also developed. It was found that powder flow properties play a significant role in roll compaction.
Original languageEnglish
Pages (from-to)1434-1435
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Volume62
Issue number10
Publication statusPublished - 1 Oct 2010

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