Experimental study on low pulse energy processing with femtosecond lasers for glaucoma treatment

D. X. Hou, D. L. Butler, L. M. He, H. Y. Zheng

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The feasibility of low energy processing in ocular tissues with femtosecond laser sources was investigated in this research. One laser source was a femtosecond amplifier, and the other was a femtosecond oscillator. The amplifier used in this experiment was a CPA-2001 (Clark-MXR, Inc), with 150 fs pulse duration and 1 kHz repetition rate. The femtosecond oscillator (model 900-B Mira) produced a 200 fs pulse duration and a 76 MHz repetition rate. Both these two laser systems operated at 800 nm wavelengths. Firstly, the pulse intensity thresholds in water produced by the two laser sources were compared. The optical breakdown probability analysis shows that the pulse energy threshold achieved by the oscillator was less than 10% of that achieved by the amplifier. Then, the non-linear propagation of the femtosecond pulses in the ocular tissues was studied with the femtosecond oscillator. The results showed a potential for pulse energy processing at the nanojoule level with a femtosecond oscillator in glaucoma treatment.

Original languageEnglish
Pages (from-to)151-154
Number of pages4
JournalLasers in Medical Science
Volume24
Issue number2
DOIs
Publication statusPublished - Mar 2009

Bibliographical note

Funding Information:
Acknowledgement Sincere thanks to Nanyang Technological University for providing the research funding for this project, and to Singapore Institute of Manufacturing (SIM Tech) for offering the femtosecond laser equipment, thus enabling us to carry out the experiment in this research.

Keywords

  • Non-linear propagation
  • Optical breakdown threshold
  • Pulse energy

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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