Abstract
Intrathymic inoculation of donor alloantigen and concomitant immunosuppressive treatment can induce immune unresponsiveness to alloantigen. To examine the role of non-deletional mechanisms in the development of unresponsiveness, fractionated splenocytes were injected into only 1 lobe of the thymus.
| Original language | English |
|---|---|
| Pages (from-to) | 576-83 |
| Number of pages | 8 |
| Journal | The Journal of Heart and Lung Transplantation |
| Volume | 19 |
| Issue number | 6 |
| Publication status | Published - Jun 2000 |
Keywords
- Animals
- Heart Transplantation
- Spleen
- Mice
- Transplantation, Homologous
- Immunosuppressive Agents
- Isoantigens
- Mice, Inbred CBA
- Graft Rejection
- Autoantibodies
- Thymus Gland
- Graft Survival
- Mice, Inbred C57BL
- Antigen-Presenting Cells
- Cell Transplantation
- Injections
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