Evidence-based assessment on environmental mixture using a concentration-dependent transcriptomics approach

Pingping Wang, Pu Xia, Zhihao Wang, Xiaowei Zhang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The CRZT approach provides a powerful tool for characterizing the effects of complex chemical mixtures.

Original languageEnglish
Article number114839
JournalEnvironmental Pollution
Volume265
DOIs
Publication statusPublished - Oct 2020

Bibliographical note

Funding Information:
For support, we thank the National Natural Science Foundation of China ( 21677072 ) and European Union Seventh Framework Programs (The SOLUTIONS project, grant 603437 ) . P.W was supported by Program B for Outstanding Ph.D. Candidates of Nanjing University (No. 201801B033 ) and Nanjing University Innovation and Creative Program for PhD candidate ( NO.CXCY17 -22 ). The research is also supported by the Fundamental Research Funds for the Central Universities . Thanks go to Professor Rolf Altenburger and Werner Brack for provision of the water samples and for helpful discussion.

Funding Information:
For support, we thank the National Natural Science Foundation of China (21677072) and European Union Seventh Framework Programs (The SOLUTIONS project, grant 603437) . P.W was supported by Program B for Outstanding Ph.D. Candidates of Nanjing University (No.201801B033) and Nanjing University Innovation and Creative Program for PhD candidate (NO.CXCY17-22). The research is also supported by the Fundamental Research Funds for the Central Universities. Thanks go to Professor Rolf Altenburger and Werner Brack for provision of the water samples and for helpful discussion.

Publisher Copyright:
© 2020 Elsevier Ltd

Keywords

  • Component-based approach
  • Effect-based methods
  • Mixture toxicity
  • Pathway-based analysis

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

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