TY - JOUR
T1 - Evaluation of the Current Models for the Evolution of Bacterial DNA Uptake Signal Sequences
AU - Chu, D
AU - Rowe, Jonathan
AU - Lee, H
PY - 2006/1/7
Y1 - 2006/1/7
N2 - Current opinion considers two main hypotheses for the evolutionary origin of uptake signal sequences in bacteria: one model regards the uptake signal sequence (USS) as the result of biased gene conversion, whereas the second model views the USS as a molecular tag that evolved as an adaptation. In this article, we present various computational models that implement specific versions of those hypotheses. Those models show that the two hypothesis are not necessarily as opposed to each other as may appear at first glance.
AB - Current opinion considers two main hypotheses for the evolutionary origin of uptake signal sequences in bacteria: one model regards the uptake signal sequence (USS) as the result of biased gene conversion, whereas the second model views the USS as a molecular tag that evolved as an adaptation. In this article, we present various computational models that implement specific versions of those hypotheses. Those models show that the two hypothesis are not necessarily as opposed to each other as may appear at first glance.
UR - http://www.scopus.com/inward/record.url?scp=28444480266&partnerID=8YFLogxK
U2 - 10.1016/j.jtbi.2005.05.024
DO - 10.1016/j.jtbi.2005.05.024
M3 - Article
C2 - 16023142
SN - 0022-5193
VL - 238
SP - 157
EP - 166
JO - Journal of Theoretical Biology
JF - Journal of Theoretical Biology
IS - 1
ER -