Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses: study protocol for a cluster randomised controlled trial

Humera Plappert; Charley Hobson-Merrett; Bliss Gibbons; Elina Baker; Sheridan Bevan; Michael Clark; Siobhan Creanor; Linda Davies; Rebecca Denyer; Julia Frost; Linda Gask; John Gibson; Laura Gill; Ruth Gwernan-Jones; Pollyanna Hardy; Joanne Hosking; Peter Huxley; Alison Jeffrey; Benjamin Jones; Steven Marwaha; Vanessa Pinold; Claire Planner; Tim Rawcliffe; Siobhan Reilly; Debra Richards; Lynsey Williams; Max Birchwood; Richard Byng

doi:10.3399/BJGPO.2021.0033

Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses: study protocol for a cluster randomised controlled trial

Humera Plappert, Charley Hobson-Merrett, Bliss Gibbons, Elina Baker, Sheridan Bevan, Michael Clark, Siobhan Creanor, Linda Davies, Rebecca Denyer, Julia Frost, Linda Gask, John Gibson, Laura Gill, Ruth Gwernan-Jones, Pollyanna Hardy, Joanne Hosking, Peter Huxley, Alison Jeffrey, Benjamin Jones, Steven MarwahaVanessa Pinold, Claire Planner, Tim Rawcliffe, Siobhan Reilly, Debra Richards, Lynsey Williams, Max Birchwood, Richard Byng

Research output: Contribution to journal › Article › peer-review

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Abstract

Background

Current NHS policy encourages an integrated approach to provision of mental and physical care for individuals with long term mental health problems. The ‘PARTNERS2’ complex intervention is designed to support individuals with psychosis in a primary care setting.

Aim

The trial will evaluate the clinical and cost-effectiveness of the PARTNERS2 intervention.

Design & setting

This is a cluster randomised controlled superiority trial comparing collaborative care (PARTNERS2) with usual care, with an internal pilot to assess feasibility. The setting will be primary care within four trial recruitment areas: Birmingham & Solihull, Cornwall, Plymouth, and Somerset. GP practices are randomised 1:1 to either (a) the PARTNERS2 intervention plus modified standard care (‘intervention’); or (b) standard care only (‘control’).

Method

PARTNERS2 is a flexible, general practice-based, person-centred, coaching-based intervention aimed at addressing mental health, physical health, and social care needs. Two hundred eligible individuals from 39 GP practices are taking part. They were recruited through identification from secondary and primary care databases. The primary hypothesis is quality of life (QOL). Secondary outcomes include: mental wellbeing, time use, recovery, and process of physical care. A process evaluation will assess fidelity of intervention delivery, test hypothesised mechanisms of action, and look for unintended consequences. An economic evaluation will estimate its cost-effectiveness. Intervention delivery and follow-up have been modified during the COVID-19 pandemic.

Conclusion

The overarching aim is to establish the clinical and cost-effectiveness of the model for adults with a diagnosis of schizophrenia, bipolar, or other types of psychoses.

Original language	English
Pages (from-to)	1-14
Number of pages	14
Journal	BJGP Open
Volume	5
Issue number	3
Early online date	30 Jun 2021
DOIs	https://doi.org/10.3399/BJGPO.2021.0033
Publication status	Published - Jun 2021

Bibliographical note

Funding Information:
PARTNERS2 is funded by the National Institute for Health Research (NIHR) under its Programme Grant for Applied Research Programme (grant number: RP-PG-200625). This research was also supported by the NIHR Collaboration for Leadership in Applied Health Research and Care South West Peninsula at the Royal Devon and Exeter NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the National Health Service (NHS), NIHR or the Department of Health. The funder had no role in the design of this study and will not have any role during execution, analysis, interpretation of findings or decision to submit results.

Publisher Copyright:
© 2021, The Authors.

Keywords

Bipolar Disorder
Collaborative Care
Protocol
Psychotic Disorders
Randomized Controlled Trial
Schizophrenia

ASJC Scopus subject areas

Family Practice

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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PlappertH2021EvaluationFinal published version, 1.15 MBLicence: Creative Commons: Attribution (CC BY)

Cite this

Plappert, H., Hobson-Merrett, C., Gibbons, B., Baker, E., Bevan, S., Clark, M., Creanor, S., Davies, L., Denyer, R., Frost, J., Gask, L., Gibson, J., Gill, L., Gwernan-Jones, R., Hardy, P., Hosking, J., Huxley, P., Jeffrey, A., Jones, B., ... Byng, R. (2021). Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses: study protocol for a cluster randomised controlled trial. BJGP Open, 5(3), 1-14. Advance online publication. https://doi.org/10.3399/BJGPO.2021.0033

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abstract = "Background Current NHS policy encourages an integrated approach to provision of mental and physical care for individuals with long term mental health problems. The {\textquoteleft}PARTNERS2{\textquoteright} complex intervention is designed to support individuals with psychosis in a primary care setting.Aim The trial will evaluate the clinical and cost-effectiveness of the PARTNERS2 intervention.Design & setting This is a cluster randomised controlled superiority trial comparing collaborative care (PARTNERS2) with usual care, with an internal pilot to assess feasibility. The setting will be primary care within four trial recruitment areas: Birmingham & Solihull, Cornwall, Plymouth, and Somerset. GP practices are randomised 1:1 to either (a) the PARTNERS2 intervention plus modified standard care ({\textquoteleft}intervention{\textquoteright}); or (b) standard care only ({\textquoteleft}control{\textquoteright}).Method PARTNERS2 is a flexible, general practice-based, person-centred, coaching-based intervention aimed at addressing mental health, physical health, and social care needs. Two hundred eligible individuals from 39 GP practices are taking part. They were recruited through identification from secondary and primary care databases. The primary hypothesis is quality of life (QOL). Secondary outcomes include: mental wellbeing, time use, recovery, and process of physical care. A process evaluation will assess fidelity of intervention delivery, test hypothesised mechanisms of action, and look for unintended consequences. An economic evaluation will estimate its cost-effectiveness. Intervention delivery and follow-up have been modified during the COVID-19 pandemic.Conclusion The overarching aim is to establish the clinical and cost-effectiveness of the model for adults with a diagnosis of schizophrenia, bipolar, or other types of psychoses.",

keywords = "Bipolar Disorder, Collaborative Care, Protocol, Psychotic Disorders, Randomized Controlled Trial, Schizophrenia",

author = "Humera Plappert and Charley Hobson-Merrett and Bliss Gibbons and Elina Baker and Sheridan Bevan and Michael Clark and Siobhan Creanor and Linda Davies and Rebecca Denyer and Julia Frost and Linda Gask and John Gibson and Laura Gill and Ruth Gwernan-Jones and Pollyanna Hardy and Joanne Hosking and Peter Huxley and Alison Jeffrey and Benjamin Jones and Steven Marwaha and Vanessa Pinold and Claire Planner and Tim Rawcliffe and Siobhan Reilly and Debra Richards and Lynsey Williams and Max Birchwood and Richard Byng",

note = "Funding Information: PARTNERS2 is funded by the National Institute for Health Research (NIHR) under its Programme Grant for Applied Research Programme (grant number: RP-PG-200625). This research was also supported by the NIHR Collaboration for Leadership in Applied Health Research and Care South West Peninsula at the Royal Devon and Exeter NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the National Health Service (NHS), NIHR or the Department of Health. The funder had no role in the design of this study and will not have any role during execution, analysis, interpretation of findings or decision to submit results. Publisher Copyright: {\textcopyright} 2021, The Authors.",

year = "2021",

month = jun,

doi = "10.3399/BJGPO.2021.0033",

language = "English",

volume = "5",

pages = "1--14",

journal = "BJGP Open",

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Plappert, H, Hobson-Merrett, C, Gibbons, B, Baker, E, Bevan, S, Clark, M, Creanor, S, Davies, L, Denyer, R, Frost, J, Gask, L, Gibson, J, Gill, L, Gwernan-Jones, R, Hardy, P, Hosking, J, Huxley, P, Jeffrey, A, Jones, B, Marwaha, S, Pinold, V, Planner, C, Rawcliffe, T, Reilly, S, Richards, D, Williams, L, Birchwood, M & Byng, R 2021, 'Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses: study protocol for a cluster randomised controlled trial', BJGP Open, vol. 5, no. 3, pp. 1-14. https://doi.org/10.3399/BJGPO.2021.0033

Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses: study protocol for a cluster randomised controlled trial. / Plappert, Humera; Hobson-Merrett, Charley; Gibbons, Bliss et al.
In: BJGP Open, Vol. 5, No. 3, 06.2021, p. 1-14.

Research output: Contribution to journal › Article › peer-review

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T1 - Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses

T2 - study protocol for a cluster randomised controlled trial

AU - Plappert, Humera

AU - Hobson-Merrett, Charley

AU - Gibbons, Bliss

AU - Baker, Elina

AU - Bevan, Sheridan

AU - Clark, Michael

AU - Creanor, Siobhan

AU - Davies, Linda

AU - Denyer, Rebecca

AU - Frost, Julia

AU - Gask, Linda

AU - Gibson, John

AU - Gill, Laura

AU - Gwernan-Jones, Ruth

AU - Hardy, Pollyanna

AU - Hosking, Joanne

AU - Huxley, Peter

AU - Jeffrey, Alison

AU - Jones, Benjamin

AU - Marwaha, Steven

AU - Pinold, Vanessa

AU - Planner, Claire

AU - Rawcliffe, Tim

AU - Reilly, Siobhan

AU - Richards, Debra

AU - Williams, Lynsey

AU - Birchwood, Max

AU - Byng, Richard

N1 - Funding Information: PARTNERS2 is funded by the National Institute for Health Research (NIHR) under its Programme Grant for Applied Research Programme (grant number: RP-PG-200625). This research was also supported by the NIHR Collaboration for Leadership in Applied Health Research and Care South West Peninsula at the Royal Devon and Exeter NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the National Health Service (NHS), NIHR or the Department of Health. The funder had no role in the design of this study and will not have any role during execution, analysis, interpretation of findings or decision to submit results. Publisher Copyright: © 2021, The Authors.

PY - 2021/6

Y1 - 2021/6

N2 - Background Current NHS policy encourages an integrated approach to provision of mental and physical care for individuals with long term mental health problems. The ‘PARTNERS2’ complex intervention is designed to support individuals with psychosis in a primary care setting.Aim The trial will evaluate the clinical and cost-effectiveness of the PARTNERS2 intervention.Design & setting This is a cluster randomised controlled superiority trial comparing collaborative care (PARTNERS2) with usual care, with an internal pilot to assess feasibility. The setting will be primary care within four trial recruitment areas: Birmingham & Solihull, Cornwall, Plymouth, and Somerset. GP practices are randomised 1:1 to either (a) the PARTNERS2 intervention plus modified standard care (‘intervention’); or (b) standard care only (‘control’).Method PARTNERS2 is a flexible, general practice-based, person-centred, coaching-based intervention aimed at addressing mental health, physical health, and social care needs. Two hundred eligible individuals from 39 GP practices are taking part. They were recruited through identification from secondary and primary care databases. The primary hypothesis is quality of life (QOL). Secondary outcomes include: mental wellbeing, time use, recovery, and process of physical care. A process evaluation will assess fidelity of intervention delivery, test hypothesised mechanisms of action, and look for unintended consequences. An economic evaluation will estimate its cost-effectiveness. Intervention delivery and follow-up have been modified during the COVID-19 pandemic.Conclusion The overarching aim is to establish the clinical and cost-effectiveness of the model for adults with a diagnosis of schizophrenia, bipolar, or other types of psychoses.

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KW - Collaborative Care

KW - Protocol

KW - Psychotic Disorders

KW - Randomized Controlled Trial

KW - Schizophrenia

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Evaluation of a primary care based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar or other psychoses: study protocol for a cluster randomised controlled trial

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this