Ergogenic effects of an epidural neuroprosthesis in one individual with spinal cord injury

Tom E Nightingale, Matthias Walter, Alison M M Williams, Tania Lam, Andrei V Krassioukov

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
114 Downloads (Pure)


Individuals with a spinal cord injury (SCI) ≥T6 level exhibit impaired cardiovascular responses to exercise that can limit exercise capacity.1 The burgeoning field of neuromodulation has recently demonstrated that epidural spinal cord stimulation (ESCS), configured to facilitate motor function in humans with SCI, can also modulate cardiovascular function (i.e., increasing or maintaining arterial blood pressure at rest or in response to an orthostatic challenge, respectively).2,–,4 Here we present a unique application of ESCS to improve upper body exercise capacity in an individual with SCI, via the modulation of cardiovascular and respiratory function.
Original languageEnglish
Pages (from-to)338-340
Number of pages3
Issue number7
Early online date11 Jan 2019
Publication statusPublished - 12 Feb 2019


  • Adult
  • Arterial Pressure
  • Blood Pressure
  • Exercise
  • Humans
  • Implantable Neurostimulators
  • Male
  • Oxygen Consumption
  • Physical Exertion
  • Quadriplegia/physiopathology
  • Respiration
  • Spinal Cord Injuries/physiopathology
  • Spinal Cord Stimulation/methods
  • Stroke Volume


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